DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brv3 and loxhd1b

DIOPT Version :9

Sequence 1:	NP_001284831.1	Gene:	brv3 / 31246	FlyBaseID:	FBgn0040333	Length:	750	Species:	Drosophila melanogaster
Sequence 2:	XP_001920640.3	Gene:	loxhd1b / 100150283	ZFINID:	ZDB-GENE-081104-370	Length:	2268	Species:	Danio rerio

Alignment Length:	247	Identity:	41/247 - (16%)
Similarity:	86/247 - (34%)	Gaps:	63/247 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 RCDKDEMDEKEERRDF-LKQRLINKRANL----------MLTSRYRNYKLNDQYKMIAHDLFIYG 133
            :.:|::.:.:|:..|. .|::..:|:.|.          ....:.:..|..|..::..::|..|.
Zfish    17 KAEKEDSEPEEDDEDSRKKKKKKSKKGNADSDDDGKKSKDKKKKKKKSKTEDYVEIYENELRNYE 81

  Fly   134 PYFLCLMCLVLVTRDQTLYHNTRIITDLFMYNHTDYTGLQEVYFLNQLFDF-------IESTLVL 191
            |        ..|...:..||..::...:.:....:..|.....|:....|:       :.|....
Zfish    82 P--------EKVENYEDEYHKKKVYEVVTITGDVNGAGTDANVFVTLFGDYGITPKLHLSSKNRT 138

  Fly   192 AFNSNSTESGSPGWAHAEQSVLLGVMR--------LRQLRVSNPQVGLGPPKFSDTYYMPDWQLP 248
            :|..|.|:                |.|        |:::|:.:...||....|.|...:.|...|
Zfish   139 SFEKNKTD----------------VFRVKTHNVGPLKKIRIEHDNTGLNASWFLDRVVVTDMNRP 187

  Fly   249 YRKLHYSDKYWRIYEPWIPIKMGFEFLDALLMNFDHVGSLN--SYPELAGYV 298
            :.:.:::...|          :..:..|.|.:. |.:|||:  ..|:...||
Zfish   188 HLRFYFACNNW----------LSRDEGDGLYVR-DLLGSLDPMDMPKYNKYV 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brv3	NP_001284831.1	PKD_channel	170..595	CDD:285288	27/146 (18%)
loxhd1b	XP_001920640.3	PLAT_repeat	96..215	CDD:238854	21/145 (14%)
		PLAT_repeat	225..342	CDD:238854	2/4 (50%)
		PLAT_repeat	349..467	CDD:238854
		PLAT_repeat	478..595	CDD:238854
		PLAT_repeat	606..727	CDD:238854
		PLAT_repeat	737..858	CDD:238854
		PLAT_repeat	867..1020	CDD:238854
		PLAT_repeat	1028..1146	CDD:238854
		PLAT_repeat	1173..1293	CDD:238854
		PLAT_repeat	1304..1431	CDD:238854
		PLAT_repeat	1458..1578	CDD:238854
		PLAT	1624..1741	CDD:294016
		PLAT_repeat	1753..1871	CDD:238854
		PLAT_repeat	1881..2001	CDD:238854
		PLAT	2014..2118	CDD:279778
		PLAT_repeat	2149..2267	CDD:238854
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900