Protein Alignment Seipin and bscl2l

DIOPT Version :9

• Sequence 1: NP_570012.1
• Gene: Seipin / 31245
• FlyBaseID: FBgn0040336
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001013571.1
• Gene: bscl2l / 541427
• ZFINID: ZDB-GENE-050320-130
• Length: 392
• Species: Danio rerio
• Alignment Length: 367
• Identity: 110/367 - (29%)
• Similarity: 192/367 - (52%)
• Gaps: 58/367 - (15%)

  Fly    32 NVYDRVRSKADEKVGTVRELV-------LRLGLIAFAVVLIIWLAVFMYAAFYYVYMPAISHTRP 89
            :|..::|....|.:.|:.:|:       :.:.:|...::|:.|:|:|:|.:|||.:||..:...|
Zfish    17 DVGPQIRGLVVEILETMSDLLVWMRRKAVEMVIIICVILLVFWVALFLYGSFYYSFMPTANFVAP 81

  Fly    90 VHMQFKTCLETSTP----CTFPHAHVSLTK--KQQLLMVGQAYKVIVNIDMPESPQNLELGMFMV 148
            |:. |.:..:..:|    |:||.|:|||.|  |.|::..||.|::.:.::|||||.|.:||||:|
Zfish    82 VNF-FHSRTDCPSPHHPMCSFPMANVSLLKNGKHQVMTYGQPYQITLKLEMPESPTNQQLGMFLV 145

  Fly   149 CAEMRDYDSMLRGHSCRSAMMRYRSPLIRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQH 213
            ..........:.|.|.||||:.|||.|::.:.|.|.||:::.|..|:.|.|.||:||.:.::...
Zfish   146 TITPYSKAGQIIGVSSRSAMLHYRSSLLQTLGTLVFSPMFLSGMSEQKQSVTVELFSEFKDDSYK 210

  Fly   214 PITDVYVEIQSQKIQFYTVTLHIVADFTGLRYIMFNWPVLSAIVAISTNLFFILVVFLLSWYHWS 278
            |.....:||.:..||.|...|:|.|.|||:||:::.:|::||::.:.||..|:.::.:||:..::
Zfish   211 PTVGAMLEIHAPNIQIYKANLYIFAHFTGIRYLLYQFPLISALMGVMTNFTFLSLIIVLSFLQFN 275

  Fly   279 DAKWLHSVQI-KYARLTKS------------LEP---GVIHSKASSLRDDDDDLVAYSDKSDIAD 327
                |:..|. :.||:.:.            .||   |:|.....::..:..|:     :..|.|
Zfish   276 ----LNGRQFRRKARMQQEEMDEIDDLFDDPSEPHDRGIIPENVDTMDCNSADM-----EESIPD 331

  Fly   328 VGGDTLSDVDADDLVLVKKSRSGKRESP--------DALRKR 361
            |.|:     |:||      ||...::.|        ..||:|
Zfish   332 VTGE-----DSDD------SRELTKDEPICEDGNEETILRRR 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Seipin	NP_570012.1	Seipin	63..262	CDD:284243	77/204 (38%)
bscl2l	NP_001013571.1	Seipin	55..259	CDD:284243	77/204 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575176
Domainoid	1	1.000	171	1.000	Domainoid score	I3694
eggNOG	1	0.900	-	-		E1_KOG4200
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3895
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1390748at2759
OrthoFinder	1	1.000	-	-		FOG0004864
OrthoInspector	1	1.000	-	-		otm25774
orthoMCL	1	0.900	-	-		OOG6_104060
Panther	1	1.100	-	-	O	PTHR21212
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R150
SonicParanoid	1	1.000	-	-		X4543
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790