Protein Alignment Seipin and Bscl2

DIOPT Version :9

• Sequence 1: NP_570012.1
• Gene: Seipin / 31245
• FlyBaseID: FBgn0040336
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001012171.2
• Gene: Bscl2 / 361722
• RGDID: 1308135
• Length: 437
• Species: Rattus norvegicus
• Alignment Length: 352
• Identity: 116/352 - (32%)
• Similarity: 194/352 - (55%)
• Gaps: 34/352 - (9%)

  Fly    46 GTVRELVLRLGLIAFAVVLIIWLAVFMYAAFYYVYMPAISHTRPVHMQFKTCLETSTP--CTFPH 108
            |..|.|:|:.|::...::|::|::||:|.:|||.|||.:||..|||..::|..::||.  |:||.
  Rat    82 GRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYYRTDCDSSTASLCSFPV 146

  Fly   109 AHVSLTK--KQQLLMVGQAYKVIVNIDMPESPQNLELGMFMVCAEMRDYDSMLRGHSCRSAMMRY 171
            |:|||||  :.::||.||.|:|.:.:::||||.|.:||||:|..........:...|.||.|:.|
  Rat   147 ANVSLTKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHY 211

  Fly   172 RSPLIRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQHPITDVYVEIQSQKIQFYTVTLHI 236
            ||.|::|:.|.|.|.|.:.|:.|:.|.:.||::|.|.|....|.|...:|:.|:::|.|...|.|
  Rat   212 RSQLLQMLDTLVFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEVHSKRVQMYGAYLRI 276

  Fly   237 VADFTGLRYIMFNWPVLSAIVAISTNLFFILVVFLLSWYHWS-DAKW---LHSVQIKYARLTKS- 296
            .|.||||||:::|:|:..|.|.:::|..|:.|:.|.|:..|. .|.|   ..|:|:...:...|
  Rat   277 HAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIALFSYMQWVWGAVWPRHRFSLQVNIRQRDNSG 341

  Fly   297 ---------LEPGVIHSKASSLRDDDDD---------LVAYSDKSDIADVGGDTLSDVDADD--- 340
                     .:||...::.|.:.:|.:.         .::..:|.:...:.|:...:.:|.|
  Rat   342 HGAQRRISRHQPGQASTQQSDVTEDGESPEDPSGTEGQLSEEEKPEKQPLNGEGEQEPEASDGSW 406

  Fly   341 ---LVLVKKSRSG-KRESPDALRKRPT 363
               .:|.:.|.|. ..|:..:||:|.|
  Rat   407 EDAALLTEASTSALAPETLGSLRQRQT 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Seipin	NP_570012.1	Seipin	63..262	CDD:284243	84/202 (42%)
Bscl2	NP_001012171.2	Seipin	99..303	CDD:399628	84/203 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3608
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3725
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1390748at2759
OrthoFinder	1	1.000	-	-		FOG0004864
OrthoInspector	1	1.000	-	-		oto97495
orthoMCL	1	0.900	-	-		OOG6_104060
Panther	1	1.100	-	-	LDO	PTHR21212
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4543
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.970