Protein Alignment Seipin and BSCL2

DIOPT Version :10

• Sequence 1: NP_570012.1
• Gene: Seipin / 31245
• FlyBaseID: FBgn0040336
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001372956.1
• Gene: BSCL2 / 26580
• HGNCID: 15832
• Length: 464
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 95/236 - (40%)
• Similarity: 151/236 - (63%)
• Gaps: 4/236 - (1%)

  Fly    46 GTVRELVLRLGLIAFAVVLIIWLAVFMYAAFYYVYMPAISHTRPVHMQFKTCLETSTP--CTFPH 108
            |..|.|:|:.|::...::|::|::||:|.:|||.|||.:||..|||..::|..::||.  |:||.
Human    86 GRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYYRTDCDSSTTSLCSFPV 150

  Fly   109 AHVSLTK--KQQLLMVGQAYKVIVNIDMPESPQNLELGMFMVCAEMRDYDSMLRGHSCRSAMMRY 171
            |:|||||  :.::||.||.|:|.:.:::||||.|.:||||:|..........:...|.||.|:.|
Human   151 ANVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHY 215

  Fly   172 RSPLIRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQHPITDVYVEIQSQKIQFYTVTLHI 236
            ||.|::|:.|.|.|.|.:.|:.|:.|.:.||:::.|.|....|.|...:||.|::||.|...|.|
Human   216 RSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRI 280

  Fly   237 VADFTGLRYIMFNWPVLSAIVAISTNLFFILVVFLLSWYHW 277
            .|.||||||:::|:|:..|.:.:::|..|:.|:.|.|:..|
Human   281 HAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQW 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Seipin	NP_570012.1	Seipin	82..242	CDD:467827	66/163 (40%)
BSCL2	NP_001372956.1	Seipin	122..286	CDD:467827	66/163 (40%)
		PHA03169	<355..>414	CDD:223003