DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Seipin and seip-1

DIOPT Version :9

Sequence 1:	NP_570012.1	Gene:	Seipin / 31245	FlyBaseID:	FBgn0040336	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_741547.1	Gene:	seip-1 / 259621	WormBaseID:	WBGene00019808	Length:	274	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	55/228 - (24%)
Similarity:	107/228 - (46%)	Gaps:	13/228 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LRLGLIAFAVVLI-IWLAVFMYAA----FYYVYMP-AISHTRPVHMQFKTC-LETSTPCTFPHAH 110
            :|.|...|...|: :.:|:|:.|.    ..|..:| ::.|...:::.|:|| .:..:.|:||.|.
Worm     1 MRFGKDCFLSTLVELSVAIFIAAVTPLLIRYCLLPSSVHHQYQLNIVFQTCDHDLHSVCSFPAAT 65

  Fly   111 VSLTKKQQLLMVGQAYKVIVNIDMPESPQNLELGMFMVCAEMRDYDSMLRGHSCRSAMMRYRSPL 175
            :.. :|..|.....||.:.|.:...:.....:||:|.....:.|.:..:.....:||.:: .:.|
Worm    66 LEY-EKNSLFSPNVAYYLNVRLKFADVINTNKLGLFQNVITITDENQKILKQYTKSAYVK-EAGL 128

  Fly   176 IRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQHPITDVYVEIQSQKIQFYTVTLHIVADF 240
            |:......|.|.|.||:..::..:.:.:.:.|||....|.|.:...:|.:........|.:.|.|
Worm   129 IQKAMHLFLFPFYFLGFFHDYSTLAIPMSADYLEGIDSPSTKLVFVVQDKFANIEEAELIVTARF 193

  Fly   241 TGLRYIMFNWPVLS-AIVAISTNLFFILVVFLL 272
            ..:|::::.||..| |.:.:||   |::.|||:
Worm   194 GLIRHLLYYWPTTSYATIFVST---FVIGVFLI 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Seipin	NP_570012.1	Seipin	63..262	CDD:284243	47/206 (23%)
seip-1	NP_741547.1	Seipin	16..216	CDD:284243	47/204 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1390748at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto18255
orthoMCL	1	0.900	-	-		OOG6_104060
Panther	1	1.100	-	-	LDO	PTHR21212
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R150
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.740