Protein Alignment Seipin and Bscl2

DIOPT Version :10

• Sequence 1: NP_570012.1
• Gene: Seipin / 31245
• FlyBaseID: FBgn0040336
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_032170.3
• Gene: Bscl2 / 14705
• MGIID: 1298392
• Length: 443
• Species: Mus musculus
• Alignment Length: 358
• Identity: 117/358 - (32%)
• Similarity: 195/358 - (54%)
• Gaps: 40/358 - (11%)

  Fly    46 GTVRELVLRLGLIAFAVVLIIWLAVFMYAAFYYVYMPAISHTRPVHMQFKTCLETSTP--CTFPH 108
            |..|.|:|:.|::...::|::|::||:|.:|||.|||.:||..|||..::|..::||.  |:||.
Mouse    82 GRARRLMLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYRTDCDSSTASLCSFPV 146

  Fly   109 AHVSLTK--KQQLLMVGQAYKVIVNIDMPESPQNLELGMFMVCAEMRDYDSMLRGHSCRSAMMRY 171
            |:|||.|  :.::||.||.|:|.:.:::||||.|.:||||:|..........:...|.||.|:.|
Mouse   147 ANVSLAKSGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHY 211

  Fly   172 RSPLIRMISTWVLSPLYVLGWKEEFQQVPVEIFSRYLEERQHPITDVYVEIQSQKIQFYTVTLHI 236
            ||.|::::.|.:.|.|.:.|:.|:.|.:.||::|.|.|....|.|...:||.|::||.|...|.|
Mouse   212 RSQLLQVLDTLLFSSLLLFGFAEQKQLLEVELYSDYRENSYVPTTGAIIEIHSKRIQMYGAYLRI 276

  Fly   237 VADFTGLRYIMFNWPVLSAIVAISTNLFFILVVFLLSWYHWS-DAKW---LHSVQIKYARLTKS- 296
            .|.||||||:::|:|:..|.|.:::|..|:.|:.|.|:..|. .|.|   ..|:|:...:...|
Mouse   277 HAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGAVWPRHRFSLQVNIRQRDNSH 341

  Fly   297 ---------LEPGVIHSKASSLRDDDDD---------LVAYSDKSDIADVGGD-----TLSDVDA 338
                     .:||...::.|.:.:|.:.         .::..:|.:...:.|:     ..||...
Mouse   342 HGAPRRISRHQPGQESTQQSDVTEDGESPEDPSGTEGQLSEEEKPEKRPLNGEEEQEPEASDGSW 406

  Fly   339 DDLVLVKK-----SRSGKRESPD---ALRKRPT 363
            :|..|:.:     |.|....:|:   :||:|||
Mouse   407 EDAALLTEANPPTSASASALAPETLGSLRQRPT 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Seipin	NP_570012.1	Seipin	82..242	CDD:467827	64/163 (39%)
Bscl2	NP_032170.3	Seipin	99..303	CDD:462007	83/203 (41%)
		PTZ00415	345..>409	CDD:185603	8/63 (13%)