Protein Alignment Tsp3A and CD151

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_004348.2
• Gene: CD151 / 977
• HGNCID: 1630
• Length: 253
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 74/275 - (26%)
• Similarity: 124/275 - (45%)
• Gaps: 56/275 - (20%)

  Fly    42 CVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFY------DVFLNISLVMILAG 100
            |:||::|..|..|||.|..::.:|::           ::.|::.|      ..:|..:.::::||
Human    15 CLKYLLFTYNCCFWLAGLAVMAVGIW-----------TLALKSDYISLLASGTYLATAYILVVAG 68

  Fly   101 TVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHS 165
            ||:.:....||....:|...||:.|.:.||:.||||:...|:.:...|.:||.|::.....:...
Human    69 TVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKR 133

  Fly   166 YRD--DPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCG--VPYSCCINATDIS 226
            |..  ...:.:.:|..||||.|||.:||  |||..:|:..    |.|..|  ||.|||
Human   134 YHQPGHEAVTSAVDQLQQEFHCCGSNNS--QDWRDSEWIR----SQEAGGRVVPDSCC------- 185

  Fly   227 SGLVNIMCG--------YGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLL 283
             ..|..:||        |.|:             .|||..:..:.:.:|.||....:|||.:|:.
Human   186 -KTVVALCGQRDHASNIYKVE-------------GGCITKLETFIQEHLRVIGAVGIGIACVQVF 236

  Fly   284 VIYLAKTLEGQIELQ 298
            .:.....|...::|:
Human   237 GMIFTCCLYRSLKLE 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	40/151 (26%)
		penumbra_like_LEL	144..267	CDD:239411	35/134 (26%)
CD151	NP_004348.2	Tetraspanin	16..246	CDD:459767	72/267 (27%)
		CD151_like_LEL	112..220	CDD:239408	35/134 (26%)