Protein Alignment Tsp3A and tspan5

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_001072198.1
• Gene: tspan5 / 779644
• XenbaseID: XB-GENE-868310
• Length: 268
• Species: Xenopus tropicalis
• Alignment Length: 288
• Identity: 115/288 - (39%)
• Similarity: 167/288 - (57%)
• Gaps: 26/288 - (9%)

  Fly    19 GRGYSGIEVHEVMHPHHFTYVSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGS--VR 81
            |:.|.|.|            ||.|:||.||..|.:|||.|...||:|::|:.:|...:|.|  ..
 Frog     3 GKHYKGPE------------VSCCIKYFIFGFNVIFWLLGITFLGVGLWAWSEKGVLSNISSITD 55

  Fly    82 LENFYDVFLNISLVMILAGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVC 146
            |..|..|:|     .::.|.|:|::.|:||:||||||||||||:|:.|.:.|.||:...::.||.
 Frog    56 LGGFDPVWL-----FLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVF 115

  Fly   147 PQYMNTFLEKQFTHKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNC--SSPSV 209
            ..::...|: .|.:..|.:||||.||||.|||.|:.::|||.  .|..||:.|.||||  ::.|.
 Frog   116 KDWIKDQLQ-FFINNNIRAYRDDIDLQNLIDFTQEYWQCCGA--FGADDWNLNIYFNCTDANASR 177

  Fly   210 EKCGVPYSCCINATDISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNA 274
            |:||||:|||  ..|.:..::|..|||.|:..|..:..:.|.|.||:.....|.:.||.::||..
 Frog   178 ERCGVPFSCC--TKDPAEDVINTQCGYDVRQKPELDQQETIHTKGCVPQFEKWLQDNLTIVAGVF 240

  Fly   275 LGIALIQLLVIYLAKTLEGQIELQKSRW 302
            :||||:|:..|.||:.|...||..::.|
 Frog   241 IGIALLQIFGICLAQNLVSDIEAVRASW 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	61/145 (42%)
		penumbra_like_LEL	144..267	CDD:239411	49/124 (40%)
tspan5	NP_001072198.1	Tetraspanin	15..258	CDD:459767	104/252 (41%)
		TM4SF9_like_LEL	113..233	CDD:239412	49/124 (40%)