Protein Alignment Tsp3A and TSPAN7

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 81/255 - (31%)
• Similarity: 126/255 - (49%)
• Gaps: 36/255 - (14%)

  Fly    39 VSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFYDVF----LNISLVMILA 99
            |..|:|.::.:.:||||:.|.:||.:||:          |.:.|..:..:.    .|...|:|..
Human    11 VITCLKTLLIIYSFVFWITGVILLAVGVW----------GKLTLGTYISLIAENSTNAPYVLIGT 65

  Fly   100 GTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVC-PQYMNTFLEKQFTHKII 163
            ||.|.:....||....|.:.::||.|:|.|.|.||.|:...|..||. .:..:||| :.:| ..:
Human    66 GTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFL-RTYT-DAM 128

  Fly   164 HSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATDISSG 228
            .:|..:.:....:|..|:...|||:.|  |.:||.:.||      :|. |:|.|||:|.||.:.
Human   129 QTYNGNDERSRAVDHVQRSLSCCGVQN--YTNWSTSPYF------LEH-GIPPSCCMNETDCNP- 183

  Fly   229 LVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLA 288
                   ..:.|..| .||| :...||.::|..:.|.|:.:|||.|.|||..||:.:.||
Human   184 -------QDLHNLTV-AATK-VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLA 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	41/148 (28%)
		penumbra_like_LEL	144..267	CDD:239411	36/123 (29%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	79/251 (31%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	36/123 (29%)