Protein Alignment Tsp3A and Tspan3

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_062767.3
• Gene: Tspan3 / 56434
• MGIID: 1928098
• Length: 253
• Species: Mus musculus
• Alignment Length: 254
• Identity: 65/254 - (25%)
• Similarity: 112/254 - (44%)
• Gaps: 38/254 - (14%)

  Fly    39 VSQC----VKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFY-DVFLNISLVMIL 98
            :.||    .|.::..||.:||...|:|..:|.|.| ..::|      .::|: ||:.....|:|:
Mouse     1 MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVF-ITYDD------YDHFFEDVYTLFPAVVII 58

  Fly    99 A-GTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKI 162
            | |.::|::...||...:||:...|..:...|||.|:.|:.:.::.:|....:...:::.. .|:
Mouse    59 AVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSI-QKV 122

  Fly   163 IHSYR--DDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCC-INATD 224
            ..:|.  :.......||:.|::..|||:.|  |.||...::|.    ..:...||.||| ..|..
Mouse   123 YKTYNGTNSDAASRAIDYVQRQLHCCGIHN--YSDWENTDWFK----ETKNQSVPLSCCRETAKS 181

  Fly   225 ISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLL 283
            .:..|.|            |..   ::..||..:|....:..|..:...||..|.||||
Mouse   182 CNGSLAN------------PSD---LYAEGCEALVVKKLQEILMHVIWAALAFAAIQLL 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	36/147 (24%)
		penumbra_like_LEL	144..267	CDD:239411	26/125 (21%)
Tspan3	NP_062767.3	Tetraspanin	9..235	CDD:459767	63/246 (26%)
		TM4SF8_like_LEL	104..210	CDD:239416	26/127 (20%)