Protein Alignment Tsp3A and tspan37

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_001292501.1
• Gene: tspan37 / 564334
• ZFINID: ZDB-GENE-070912-550
• Length: 245
• Species: Danio rerio
• Alignment Length: 297
• Identity: 68/297 - (22%)
• Similarity: 122/297 - (41%)
• Gaps: 84/297 - (28%)

  Fly    16 MAGGRGYSGIEVHEVMHPHHFTYVSQCVKYMIFLLNFVFWLFGGLLL-GIGVYAFRDKWEDANGS 79
            ||..||..|:.:.              :..::|||..:..|.|..|| ...||           .
Zfish     1 MALNRGAIGLFLK--------------ITCLLFLLTGITGLGGSFLLHKYRVY-----------G 40

  Fly    80 VRLENFYDVFLNISLVMILAGTVIFLVSFSGCVGALRENTFLLKFYSMC---LLLFFLLEMAIAI 141
            :...|.|.:|  .:|:.:::|.::|:....||:.:.::.:        |   |.::||    |.:
Zfish    41 LFFSNLYIIF--PALLAVVSGAILFITGSIGCLVSSKKPS--------CGHGLFVYFL----IIV 91

  Fly   142 VCFV-----CPQYMNTFLEKQFT--HKIIHSYRD---DPDLQNFIDFAQQEFKCCGLSNSGYQDW 196
            .|.|     ...:....|:.:..  ..:..:|.:   |||.: .:|..|.|.:|||:.|  |.||
Zfish    92 FCVVGTTAALAYFYQGKLDAELAPLKDVFQNYSNNSQDPDTK-AVDRLQSELQCCGVMN--YTDW 153

  Fly   197 SKNEYFNCSSPSVEKCGVPYSCCINATDISSGLVNIMCGYGVQNAPVPEATKLIWTSGC---IEI 258
            .:..:||.|.    |..||.||| |.|..|       |. |..:||:     |::...|   ::.
Zfish   154 LQTPWFNHSG----KYDVPQSCC-NTTFHS-------CN-GTLDAPM-----LLYNEACQVKLKE 200

  Fly   259 VRVWAEHNLYVIAGNALGIALIQLLVIYLAKTLEGQI 295
            :.:...|.:::       .:|:.|:::.|:....||:
Zfish   201 LLLLVVHIIHI-------TSLVVLVLLVLSWITVGQL 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	33/157 (21%)
		penumbra_like_LEL	144..267	CDD:239411	35/135 (26%)
tspan37	NP_001292501.1	Tetraspanin	14..>146	CDD:459767	33/157 (21%)
		TM4SF8_like_LEL	102..195	CDD:239416	32/113 (28%)