Protein Alignment Tsp3A and Tspan33

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_001102697.1
• Gene: Tspan33 / 500065
• RGDID: 1560915
• Length: 283
• Species: Rattus norvegicus
• Alignment Length: 265
• Identity: 108/265 - (40%)
• Similarity: 171/265 - (64%)
• Gaps: 14/265 - (5%)

  Fly    36 FTYVSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFYDVFLNISLVMILAG 100
            |::||..|||::|..|.:||:...:::.:||||...|..:|..:.       :.::.::::|:.|
  Rat    15 FSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALAC-------LAVDPAILLIVVG 72

  Fly   101 TVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHS 165
            .::||::|.||:|:||||..||:.:|:||.:.|||::|..|:.||........:.:...:.|:|
  Rat    73 VLMFLLTFCGCIGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH- 136

  Fly   166 YRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCS--SPSVEKCGVPYSCCINATDISSG 228
            ||||.||||.|||.|::|.|||  ...|:|||:|.|||||  :||.|:|.||||||:...  :..
  Rat   137 YRDDLDLQNLIDFGQKKFSCCG--GISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTP--NQA 197

  Fly   229 LVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLAKTLEG 293
            ::|.|||.|:|.....||:|:|:|:|||:.:..|...||:::.|.|||:|:.||:.|.|::.|..
  Rat   198 VINTMCGQGMQALDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVN 262

  Fly   294 QIELQ 298
            ||:.|
  Rat   263 QIKDQ 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	53/143 (37%)
		penumbra_like_LEL	144..267	CDD:239411	55/124 (44%)
Tspan33	NP_001102697.1	Tetraspanin	22..262	CDD:459767	102/251 (41%)
		penumbra_like_LEL	116..236	CDD:239411	55/124 (44%)