Protein Alignment Tsp3A and TSPAN11

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: XP_011518981.1
• Gene: TSPAN11 / 441631
• HGNCID: 30795
• Length: 302
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 63/244 - (25%)
• Similarity: 110/244 - (45%)
• Gaps: 28/244 - (11%)

  Fly    43 VKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANG--SVRLENFYDVFLNISLVMILAGTVIFL 105
            :||::|:.||.||:.|..:|.:|::...:|    :|  ||...:   .|...:.::|.||.::.:
Human    16 LKYLLFVFNFFFWVGGAAVLAVGIWTLVEK----SGYLSVLASS---TFAASAYILIFAGVLVMV 73

  Fly   106 VSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHSYRDD- 169
            ..|.|....|.|....|..|...||:.||:|:...::..|..|.::..|::.....:..:|...
Human    74 TGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQPG 138

  Fly   170 -PDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATDISSGLVNIM 233
             ..:...:|..||:|||||.::|.  ||..:.|....  ..|...||.|||        ..|.:.
Human   139 ATQITASVDRLQQDFKCCGSNSSA--DWQHSTYILLR--EAEGRQVPDSCC--------KTVVVR 191

  Fly   234 CGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQL 282
            ||   |.|......|:  ..||:..:..:...:|.::....:|:|.:|:
Human   192 CG---QRAHPSNIYKV--EGGCLTKLEQFLADHLLLMGAVGIGVACLQI 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	39/147 (27%)
		penumbra_like_LEL	144..267	CDD:239411	30/124 (24%)
TSPAN11	XP_011518981.1	Tetraspanin	16..>158	CDD:459767	40/148 (27%)
		CD151_like_LEL	112..220	CDD:239408	30/124 (24%)