Protein Alignment Tsp3A and tspan12

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_957446.1
• Gene: tspan12 / 394127
• ZFINID: ZDB-GENE-040426-1285
• Length: 301
• Species: Danio rerio
• Alignment Length: 272
• Identity: 65/272 - (23%)
• Similarity: 112/272 - (41%)
• Gaps: 59/272 - (21%)

  Fly    41 QCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDA---NGSVRLE-----NFYDVFLNISLVMI 97
            :|::.:::.|||:|||....:||:..| .||:..:.   ....|||     .:..|   :..|:|
Zfish     8 KCLRCLLYALNFLFWLMALCVLGVSAY-LRDQLNNVLTLTADTRLEEAAVRTYSPV---VHPVVI 68

  Fly    98 LAGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNT---FLEKQFT 159
            .....:.:|:..|..|.|:.|..||.:|...|::.|.:|:|..:..:..|....:   .|:.:..
Zfish    69 AVCCFLIIVAMVGYCGTLKCNLLLLSWYFGSLMVIFCVELASGVWTYDEPMVQRSDMISLKSRMP 133

  Fly   160 HKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINA-- 222
            |..:..|:   .|.:..:..|.|.||||:..  :.||.:         ..|....|.|||.|.
Zfish   134 HFGLQRYQ---WLTHAWNALQTELKCCGVIY--FTDWLE---------MTEMEWPPDSCCSNQYP 184

  Fly   223 --------TDISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIAL 279
                    .|:|. |....||        |:....|..:..::::|         ..|.::|:|
Zfish   185 GCARQAHYNDLSD-LYQEGCG--------PKIYSFIRGTKQLQVLR---------FLGVSIGVA- 230

  Fly   280 IQLLVIYLAKTL 291
             |:|.:.|..||
Zfish   231 -QILAMTLTVTL 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	38/154 (25%)
		penumbra_like_LEL	144..267	CDD:239411	27/135 (20%)
tspan12	NP_957446.1	Tetraspanin	10..243	CDD:459767	64/270 (24%)
		TM4SF12_like_LEL	113..215	CDD:239410	26/124 (21%)