Protein Alignment Tsp3A and Tspan5

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_001004090.2
• Gene: Tspan5 / 362048
• RGDID: 1303176
• Length: 268
• Species: Rattus norvegicus
• Alignment Length: 288
• Identity: 115/288 - (39%)
• Similarity: 165/288 - (57%)
• Gaps: 26/288 - (9%)

  Fly    19 GRGYSGIEVHEVMHPHHFTYVSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGS--VR 81
            |:.|.|.|            ||.|:||.||..|.:||..|...||||::|:.:|...:|.|  ..
  Rat     3 GKHYKGPE------------VSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITD 55

  Fly    82 LENFYDVFLNISLVMILAGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVC 146
            |..|..|:|     .::.|.|:|::.|:||:||||||||||||:|:.|.:.|.||:...::.||.
  Rat    56 LGGFDPVWL-----FLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVF 115

  Fly   147 PQYMNTFLEKQFTHKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNC--SSPSV 209
            ..::...| ..|.:..|.:||||.||||.|||.|:.::|||.  .|..||:.|.||||  |:.|.
  Rat   116 KDWIKDQL-YFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGA--FGADDWNLNIYFNCTDSNASR 177

  Fly   210 EKCGVPYSCCINATDISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNA 274
            |:||||:|||  ..|.:..::|..|||..:..|..:...:|:|.||:.....|.:.||.::||..
  Rat   178 ERCGVPFSCC--TKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIF 240

  Fly   275 LGIALIQLLVIYLAKTLEGQIELQKSRW 302
            :||||:|:..|.||:.|...||..::.|
  Rat   241 IGIALLQIFGICLAQNLVSDIEAVRASW 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	61/145 (42%)
		penumbra_like_LEL	144..267	CDD:239411	49/124 (40%)
Tspan5	NP_001004090.2	Tetraspanin	15..258	CDD:459767	104/252 (41%)
		TM4SF9_like_LEL	113..233	CDD:239412	49/124 (40%)