Protein Alignment Tsp3A and TSPAN33

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 109/265 - (41%)
• Similarity: 170/265 - (64%)
• Gaps: 14/265 - (5%)

  Fly    36 FTYVSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFYDVFLNISLVMILAG 100
            |::||..|||::|..|.:||:...:::.:||||...|..:|..:.       :.::.::::|:.|
Human    15 FSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALAC-------LAVDPAILLIVVG 72

  Fly   101 TVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHS 165
            .::||::|.||:|:||||..||:.:|:||...|||::|..|:.||........:.:...:.|:|
Human    73 VLMFLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH- 136

  Fly   166 YRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCS--SPSVEKCGVPYSCCINATDISSG 228
            ||||.||||.|||.|::|.|||  ...|:|||:|.|||||  :||.|:|.||||||:...|  ..
Human   137 YRDDLDLQNLIDFGQKKFSCCG--GISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPD--QA 197

  Fly   229 LVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLAKTLEG 293
            ::|.|||.|:|.....||:|:|:|:|||:.:..|...||:::.|.|||:|:.||:.|.|::.|..
Human   198 VINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVN 262

  Fly   294 QIELQ 298
            ||:.|
Human   263 QIKDQ 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	53/143 (37%)
		penumbra_like_LEL	144..267	CDD:239411	56/124 (45%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	103/251 (41%)
		penumbra_like_LEL	116..236	CDD:239411	56/124 (45%)