Protein Alignment Tsp3A and Tspan6

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_001094142.1
• Gene: Tspan6 / 302313
• RGDID: 1560160
• Length: 245
• Species: Rattus norvegicus
• Alignment Length: 273
• Identity: 80/273 - (29%)
• Similarity: 125/273 - (45%)
• Gaps: 64/273 - (23%)

  Fly    39 VSQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLENFYDVF----LNISLVMILA 99
            |..|.|.::.:..|:||:.|.:||.:|::          |.|.|||::.:.    .|:..|:|..
  Rat    13 VITCFKSVLLIYTFIFWITGVILLAVGIW----------GKVSLENYFSLLNEKATNVPFVLIGT 67

  Fly   100 GTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIH 164
            ||||.|:...||....|.:.::||.|:|.|.|.||:|:..|||.||            |.|:|.:
  Rat    68 GTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFV------------FRHEIKN 120

  Fly   165 SYRDDPD--LQNF----------IDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYS 217
            |::.:.:  |:.:          :|..|....|||::|  |:||....|::       :.|.|.|
  Rat   121 SFKSNYENALKEYNSTRDYRSEAVDKIQSTLHCCGVTN--YRDWKGTNYYS-------ETGFPKS 176

  Fly   218 CCINATDISSGLVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQL 282
            ||           .:...|     |..:|.| :...||...|....|..:.|:||.:.|:|..||
  Rat   177 CC-----------KLEGCY-----PQRDADK-VNEEGCFIKVMTTIESEMGVVAGISFGVACFQL 224

  Fly   283 LVIYLAKTLEGQI 295
            :.|:||..|...|
  Rat   225 IGIFLAYCLSRAI 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	46/159 (29%)
		penumbra_like_LEL	144..267	CDD:239411	30/134 (22%)
Tspan6	NP_001094142.1	Tetraspanin	17..235	CDD:459767	77/265 (29%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	30/134 (22%)