Protein Alignment Tsp3A and Tspan12

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_766595.1
• Gene: Tspan12 / 269831
• MGIID: 1889818
• Length: 305
• Species: Mus musculus
• Alignment Length: 266
• Identity: 61/266 - (22%)
• Similarity: 106/266 - (39%)
• Gaps: 44/266 - (16%)

  Fly    41 QCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDA---NGSVRLEN--FYDVFLNISLVMILAG 100
            :|::.:::.||.:|||....:|.:..: .||...:.   ....|:|.  ....|..:..|||...
Mouse     8 KCLRCLLYALNLLFWLMSISVLAVSAW-MRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVC 71

  Fly   101 TVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCF-----VCPQYMN-TFLEKQFT 159
            ..:.:|...|..|.::.|..||.:|...||:.|.:|:|..:..:     |..|:.: ..|:.:.|
Mouse    72 CFLIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVMVPVQWSDMVTLKARMT 136

  Fly   160 HKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATD 224
            :..:..||   .|.:..::.|:||||||:..  :.||.:         ..|....|.|||:....
Mouse   137 NYGLPRYR---WLTHAWNYFQREFKCCGVVY--FTDWLE---------MTEMDWPPDSCCVREFP 187

  Fly   225 ISSGLVNIMCGYGVQNAPVPEATKLIWTSGC----IEIVRVWAEHNLYVIAGNALGIALIQLLVI 285
                        |.......|....::..||    ...:|  ....|.|:....:.|.:.|:|.:
Mouse   188 ------------GCSKQAHQEDLSDLYQEGCGKKMYSFLR--GTKQLQVLRFLGISIGVTQILAM 238

  Fly   286 YLAKTL 291
            .|..||
Mouse   239 ILTITL 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	38/154 (25%)
		penumbra_like_LEL	144..267	CDD:239411	26/132 (20%)
Tspan12	NP_766595.1	Tetraspanin	10..246	CDD:459767	60/264 (23%)
		TM4SF12_like_LEL	116..218	CDD:239410	26/129 (20%)