Protein Alignment Tsp3A and Rom1

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_033099.3
• Gene: Rom1 / 19881
• MGIID: 97998
• Length: 351
• Species: Mus musculus
• Alignment Length: 311
• Identity: 77/311 - (24%)
• Similarity: 112/311 - (36%)
• Gaps: 100/311 - (32%)

  Fly    47 IFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLE-NFYDVFLNISL-------VMILAGTVI 103
            |:||:::..|.|||.|            ..:|.:.:: .....||..|.       ..:.||||.
Mouse    21 IWLLSWLLALVGGLTL------------LCSGHLLVQLGHLGTFLAPSCSFPALPQTALAAGTVA 73

  Fly   104 FLVSFSGCVGALREN-------------TFLLKFYSMC--LLLFFLLEMAIAIVCFVCPQYMNTF 153
            ......| .||.|.:             |.||...:..  .||...|.:|:|:     |..:|..
Mouse    74 LGTGLGG-AGASRASLDAAQYPPWRGVLTPLLAVGTAAGGGLLTLALGLALAL-----PVSLNQG 132

  Fly   154 LEKQFTHKIIHSYRDDP-----DLQNFIDFAQQEFKCCGLSNSGYQD-----WSKNEYFNCSSPS 208
            ||:.....:.| |:|..     ..:..:|..|..:.|||  ..||:|     |..|.|.:.|...
Mouse   133 LEEGLEAALAH-YKDTEVPGRCQAKRLMDELQLRYHCCG--RHGYKDWFGVQWVSNRYLDPSDQD 194

  Fly   209 VEK------------CGVPYSCCINATD---ISSGLVNIMCGYGVQNAPVPEATKL--------- 249
            |..            .|||:|||...:.   :.|.|.:            |.|..|
Mouse   195 VVDRIQSNVEGLYLIDGVPFSCCNPHSPRPCLQSQLSD------------PYAHPLFDPRQPNLN 247

  Fly   250 IWTSGCIEIVRVWAEH--NLYVIAGNALGIA-LIQLLVI----YLAKTLEG 293
            :|..||.|::   .||  .|....|:.|.:. |:|:||:    ||...|||
Mouse   248 LWAQGCHEVL---LEHLQGLSGTLGSILAVTLLLQILVLLGLRYLQTALEG 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	38/167 (23%)
		penumbra_like_LEL	144..267	CDD:239411	37/158 (23%)
Rom1	NP_033099.3	peripherin_like_LEL	128..264	CDD:239415	36/153 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	329..351