Protein Alignment Tsp3A and tsp-7

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_492636.1
• Gene: tsp-7 / 192062
• WormBaseID: WBGene00006633
• Length: 232
• Species: Caenorhabditis elegans
• Alignment Length: 260
• Identity: 69/260 - (26%)
• Similarity: 112/260 - (43%)
• Gaps: 52/260 - (20%)

  Fly    43 VKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSV---RLENFYDVF----LNISLVMILAG 100
            |||::||.|.|.|: |||.|.|            .||:   :.:|..|:.    |...:::::.|
 Worm     9 VKYLLFLANLVLWV-GGLSLII------------VGSILQLKFDNVLDILGDERLATPILLLVIG 60

  Fly   101 TVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHS 165
            ::..|:.|.||.||:|||..|...:::.|.|....|:|..|:.:.........:..|....::.
 Worm    61 SLCTLLGFLGCCGAIRENYCLTVSFAVLLALLITCEIAAVIIGYALHDSFRLGIGNQLQTGMVR- 124

  Fly   166 YRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATDISSGLV 230
            |.:...:::..|...|.|:|||::||  .||            :....:|.||||...:
 Worm   125 YHESRGVESAWDKTHQLFECCGVTNS--SDW------------LTFTTIPDSCCIEEIE------ 169

  Fly   231 NIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLAKTLEGQI 295
                |...:|||       ::..|||..|..|...|..::.|....:|.|||:.:..|..|...|
 Worm   170 ----GCARENAP-------LFEPGCIHSVEQWVLKNGAMVGGICAVLAAIQLVGVCFACCLSKSI 223

  Fly   296  295
             Worm   224  223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	40/150 (27%)
		penumbra_like_LEL	144..267	CDD:239411	26/122 (21%)
tsp-7	NP_492636.1	Tetraspanin	9..221	CDD:459767	68/256 (27%)
		NET-5_like_LEL	104..195	CDD:239418	26/122 (21%)