Protein Alignment Tsp3A and tsp-12

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_501853.1
• Gene: tsp-12 / 177890
• WormBaseID: WBGene00006638
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 280
• Identity: 98/280 - (35%)
• Similarity: 158/280 - (56%)
• Gaps: 25/280 - (8%)

  Fly    39 VSQCVKYMIFLLNFVFWLFG-GLLLGIGVYAFRDKWEDANGSVRLENFYDVFLNISLVMILAGTV 102
            :|.||||.:|..|.:|:|.| |||| .||:|..:|....|   .|.....::|:.:..:::.|.:
 Worm    34 ISCCVKYSVFSFNVIFFLLGFGLLL-FGVWAQIEKNTFVN---MLSKASKLYLDPTWPLLIVGFL 94

  Fly   103 IFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKIIHSYR 167
            .|::.||||||:|||||..|.|||..|.|..:.|.:..:..:.|...::.:: :...:.::..||
 Worm    95 TFIIGFSGCVGSLRENTSFLTFYSTLLGLLLIAEFSAGVFAYACRDQLDNYI-RNLLNDVVVGYR 158

  Fly   168 DDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSV---EKCGVPYSCCINATDISSGL 229
            ||||||..||..|:.:.|||:  :|..||.:|.||:..:..|   |..|||:|||||::.:.  .
 Worm   159 DDPDLQLLIDSMQETWMCCGI--NGADDWDRNTYFSIEAREVASPEAGGVPFSCCINSSKLE--F 219

  Fly   230 VNIMCGYGVQNAP------------VPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQL 282
            .|..||:||:..|            |...|..|:|.||:..:::|..:|:.::|.:.:.||:||:
 Worm   220 KNYFCGHGVRLKPESHMAAHLAAQRVMAHTASIYTEGCLPKLQLWLNNNMLLVAVSMVIIAIIQV 284

  Fly   283 LVIYLAKTLEGQIELQKSRW 302
            |.|..|:.|:..|..|:::|
 Worm   285 LGICFAQNLKSDILAQRAKW 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	52/144 (36%)
		penumbra_like_LEL	144..267	CDD:239411	44/137 (32%)
tsp-12	NP_501853.1	Tetraspanin	38..293	CDD:459767	92/263 (35%)
		tetraspanin_LEL	133..268	CDD:351888	44/139 (32%)