Protein Alignment Tsp3A and Tspan8

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_598210.1
• Gene: Tspan8 / 171048
• RGDID: 621783
• Length: 235
• Species: Rattus norvegicus
• Alignment Length: 262
• Identity: 69/262 - (26%)
• Similarity: 126/262 - (48%)
• Gaps: 38/262 - (14%)

  Fly    39 VSQCVKYMIFLLNFVFWLFGGLLLGIGVY--AFRDKWEDANGSVRLENFYDVFLNISLVMILAGT 101
            ||.|:||.:|..||:||:.|.|:||:.::  ..:|..|.....   :|..:.|:.:: ::|..|:
  Rat     4 VSGCLKYSMFFFNFLFWVCGTLILGLAIWLRVSKDGKEIITSG---DNGTNPFIAVN-ILIAVGS 64

  Fly   102 VIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHK---II 163
            :|.::.|.||.||::|:..:|..:.:.|||..||::|..|:........:..|.:.....   :.
  Rat    65 IIMVLGFLGCCGAVKESRCMLLLFFIGLLLILLLQVAAGILGATFKSESSRILNETLYENAKLLS 129

  Fly   164 HSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATDISSG 228
            .:..:..::|..:...|.||||||| ..|..||.||      .|..::     ||....:|..|
  Rat   130 ETSNEAKEVQKAMIAFQSEFKCCGL-RFGAADWGKN------FPDAKE-----SCQCTGSDCES- 181

  Fly   229 LVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLAKTLEG 293
                   |..:|         ::.:.|:.:::...|.|:.::.|.|.|:|:|::|.:..:..|..
  Rat   182 -------YNGEN---------VYRTTCLSLIKELVEKNIIIVIGIAFGLAVIEILGLVFSMVLYC 230

  Fly   294 QI 295
            ||
  Rat   231 QI 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	39/148 (26%)
		penumbra_like_LEL	144..267	CDD:239411	24/125 (19%)
Tspan8	NP_598210.1	Tetraspanin	8..230	CDD:459767	64/254 (25%)
		TM4SF3_like_LEL	106..204	CDD:239407	24/126 (19%)