Protein Alignment Tsp3A and Cd81

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_598416.1
• Gene: Cd81 / 12520
• MGIID: 1096398
• Length: 236
• Species: Mus musculus
• Alignment Length: 262
• Identity: 66/262 - (25%)
• Similarity: 113/262 - (43%)
• Gaps: 52/262 - (19%)

  Fly    40 SQCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVRLEN------FYDVFLNISLVMIL 98
            ::|:||::|:.||||||.||::||:.::...|....:...:.|.|      ||   :.| .::|.
Mouse     7 TKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTSLLYLELGNKPAPNTFY---VGI-YILIA 67

  Fly    99 AGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFTHKII 163
            .|.|:..|.|.||.||::|:..||..:..||::.|..|:|..|..||....:...: |||..:.:
Mouse    68 VGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDV-KQFYDQAL 131

  Fly   164 HSYRDDPDLQN---FIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATDI 225
            .....|.|..|   .:....:...||| ||:                              .|.:
Mouse   132 QQAVMDDDANNAKAVVKTFHETLNCCG-SNA------------------------------LTTL 165

  Fly   226 SSGLV-NIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVIYLAK 289
            ::.:: |.:|..| .|...|     :....|.:.:.......||:|...|:.:|:|.:..:.|:.
Mouse   166 TTTILRNSLCPSG-GNILTP-----LLQQDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSM 224

  Fly   290 TL 291
            .|
Mouse   225 VL 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	46/152 (30%)
		penumbra_like_LEL	144..267	CDD:239411	20/126 (16%)
Cd81	NP_598416.1	Tetraspanin	10..228	CDD:459767	65/259 (25%)