Protein Alignment Tsp3A and TSPAN2

DIOPT Version :10

• Sequence 1: NP_525054.2
• Gene: Tsp3A / 31244
• FlyBaseID: FBgn0040334
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 166
• Identity: 46/166 - (27%)
• Similarity: 77/166 - (46%)
• Gaps: 32/166 - (19%)

  Fly    41 QCVKYMIFLLNFVFWLFGGLLLGIGVYAFRDKWEDANGSVR--------LENFYDVFLNISL-VM 96
            :|:||::...|.:|||.|..::..|:      |....|:::        .|.||     :.| |:
Human     9 RCIKYLLLGFNLLFWLAGSAVIAFGL------WFRFGGAIKELSSEDKSPEYFY-----VGLYVL 62

  Fly    97 ILAGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCF----VCPQYMNTFLEKQ 157
            :.||.::..|.|.||.||:||:..:|..:..|||:.|..|:...:..|    |..:::.|..|:.
Human    63 VGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEA 127

  Fly   158 FTHKIIHSYRDDPDLQN--FIDFAQQEFKCCGLSNS 191
            :     :.|..|....|  .|.| ...|:|||..:|
Human   128 Y-----NDYLKDRGKGNGTLITF-HSTFQCCGKESS 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_525054.2	Tetraspanin	43..>187	CDD:459767	42/158 (27%)
		penumbra_like_LEL	144..267	CDD:239411	14/54 (26%)
TSPAN2	NP_005716.2	Tetraspanin	11..212	CDD:459767	45/164 (27%)
		CD81_like_LEL	110..186	CDD:239404	14/54 (26%)