DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp3A and tspan15

DIOPT Version :9

Sequence 1:	NP_001245504.1	Gene:	Tsp3A / 31244	FlyBaseID:	FBgn0040334	Length:	304	Species:	Drosophila melanogaster
Sequence 2:	NP_001017773.1	Gene:	tspan15 / 100000710	ZFINID:	ZDB-GENE-050417-295	Length:	296	Species:	Danio rerio

Alignment Length:	273	Identity:	98/273 - (35%)
Similarity:	140/273 - (51%)	Gaps:	32/273 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 VSQCVKYMIFLLNF-------VFWLFGGLLLGIGVYA--FRDKWEDANGSVRLENFYDVFLNISL 94
            |..|.|...|.|.|       :|||.||.:|.||:||  .|.:::...|         |||..::
Zfish     5 VRYCEKCSYFFLKFSLIGYATIFWLIGGFILAIGIYAEVERQRYKTLEG---------VFLAPAI 60

  Fly    95 VMILAGTVIFLVSFSGCVGALRENTFLLKFYSMCLLLFFLLEMAIAIVCFVCPQYMNTFLEKQFT 159
            ::|:.|.::|:|||.|.:.:||:|..|||.:...|.|..:||:...||..:........|.|...
Zfish    61 ILIVLGIIMFIVSFIGVLASLRDNLCLLKVFLYMLALCLVLELVGGIVALIFKNQTVDILNKNIR 125

  Fly   160 HKIIHSYRDDPDLQNFIDFAQQEFKCCGLSNSGYQDWSKNEYFNCSSPSVEKCGVPYSCCINATD 224
            ..:: :|.||.|.:|.:||.|:.|||||  .:.||||..|.|.|||:|....|..||:|||
Zfish   126 KGMV-NYYDDLDFKNIMDFVQKTFKCCG--GTEYQDWEVNMYHNCSAPGPLACAAPYTCCI---- 183

  Fly   225 ISSG-LVNIMCGYGVQNAPVPEATKLIWTSGCIEIVRVWAEHNLYVIAGNALGIALIQLLVI--- 285
            ::.| :||.||||...|....|.|.:|:..||.:.|.:|...|...:||..|||.|.|...:
Zfish   184 VTPGEVVNTMCGYKTLNKDRHENTDVIYIRGCTDAVFIWLIDNYKTMAGLLLGIFLPQFFGVIFT 248

  Fly   286 --YLAKTLEGQIE 296
              |:.: :|..||
Zfish   249 WLYITR-VEDAIE 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp3A	NP_001245504.1	Tetraspannin	42..295	CDD:278750	95/267 (36%)
Tsp3A	NP_001245504.1	penumbra_like_LEL	144..267	CDD:239411	46/123 (37%)
tspan15	NP_001017773.1	Tetraspannin	16..252	CDD:278750	90/251 (36%)
		MgtE	<54..>113	CDD:280023	22/58 (38%)
		penumbra_like_LEL	110..227	CDD:239411	46/123 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1416189at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920