DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and EIF3G2

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_196219.3	Gene:	EIF3G2 / 830487	AraportID:	AT5G06000	Length:	308	Species:	Arabidopsis thaliana

Alignment Length:	284	Identity:	100/284 - (35%)
Similarity:	157/284 - (55%)	Gaps:	27/284 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ETIKSSWA--DEVELDYGGLPPTTETV---ENGQKYVTEYKYNKDDKKTKVVRTYKISKQVVPKT 64
            :|.|..|.  ||.|.||..|.|..:.:   :||.|.|.|||:|::|||.|:..|.::.|:.:.|.
plant     8 KTKKLRWGEIDEEEGDYDFLLPPKQMISPDQNGVKKVIEYKFNEEDKKVKITTTTRVQKRALTKQ 72

  Fly    65 VAKRRTWTKFGDSKNDKPGPNSQTTMVS-EEIIMQFL-----NSKEDEKANDPLLD---PTKNIA 120
            ..:||:|.||||:.:::  .:|..||.| |:||::.:     |:::...:.|.:..   |...:.
plant    73 AVERRSWNKFGDAAHEE--SSSYLTMRSTEDIILERIRAPGSNAEQSTVSGDSMSQLGKPGAVLM 135

  Fly   121 KCRIC--NGEHWSVNCPYKG--TAMDTNMMEKKASAAAAAAVDAPKSGKYVPPFLK---DSQKGA 178
            .||:|  .|:||:..||.|.  :.||    |...:..:.:.:.......||||.::   |.:.|.
plant   136 VCRLCQKKGDHWTSRCPQKDLLSLMD----EPLTAETSTSTITGTGRAAYVPPSMREGADRKAGG 196

  Fly   179 LGMRGRDDTAAIRISNLSESMTEADLEELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAA 243
            ..||.|.|..::|::||||.....||.||.:..|..::.::|.|:.|.:.:||.:|.|..|:||.
plant   197 SDMRSRHDENSVRVTNLSEDTRGPDLMELFRPFGAVTRCHVAIDQKTSMSRGFGFVSFVSREDAQ 261

  Fly   244 AAIEILNGHGYDHLILSVEWSKPQ 267
            .||..|||:|||:|||.||||.|:
plant   262 RAINKLNGYGYDNLILRVEWSTPK 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	41/122 (34%)
		RRM	<161..>269	CDD:223796	46/110 (42%)
		RRM_eIF3G_like	189..265	CDD:240854	34/75 (45%)
EIF3G2	NP_196219.3	eIF3g	36..157	CDD:289149	41/122 (34%)
		RRM	<187..>287	CDD:223796	42/99 (42%)
		RRM_eIF3G_like	207..282	CDD:240854	33/74 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3145
eggNOG	1	0.900	-	-		E1_KOG0122
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I1585
OMA	1	1.010	-	-		QHG55427
OrthoDB	1	1.010	-	-		D1226059at2759
OrthoFinder	1	1.000	-	-		FOG0003558
OrthoInspector	1	1.000	-	-		mtm1122
orthoMCL	1	0.900	-	-		OOG6_102687
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2433
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.780