DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and ncbp2

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001006879.1	Gene:	ncbp2 / 448671	XenbaseID:	XB-GENE-1005786	Length:	153	Species:	Xenopus tropicalis

Alignment Length:	115	Identity:	36/115 - (31%)
Similarity:	50/115 - (43%)	Gaps:	12/115 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 AVDAPKSGKYVPPFLKDSQKGALGMRG-RDD-------TAAIRISNLSESMTEADLEELVKKIGP 213
            |:.|.||..||    :.||......|| |.|       :..:.:.|||...||..:.||..|.|.
Frog     2 ALGALKSDSYV----ELSQYRDQHFRGNRSDQECLLKHSCTLYVGNLSFYTTEEQIHELFSKSGD 62

  Fly   214 QSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEW 263
            ..|:.:..||......||.:|.:..|.||..|:..:||...|..|:..:|
Frog    63 VKKIVMGLDKIKKTACGFCFVEYYTRTDAEQAMRFINGTRLDDRIIRTDW 112

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149
		RRM	<161..>269	CDD:223796	34/111 (31%)
		RRM_eIF3G_like	189..265	CDD:240854	24/75 (32%)
ncbp2	NP_001006879.1	RRM_NCBP2	39..116	CDD:240686	24/74 (32%)
		mRNA cap-binding. /evidence=ECO:0000250	109..113		1/4 (25%)
		mRNA cap-binding. /evidence=ECO:0000250	120..124
		mRNA cap-binding. /evidence=ECO:0000250	130..131
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910