DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and Rox8

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	40/177 - (22%)
Similarity:	73/177 - (41%)	Gaps:	26/177 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 VSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNMMEKKASAAAA 155
            |||::::...::          :.|.|:   |:|.....   |.||.       .:|.....||.
  Fly    18 VSEDLLIALFST----------MGPVKS---CKIIREPG---NDPYA-------FIEYSNYQAAT 59

  Fly   156 AAVDAPKSGKYVPPFLKDSQKGALGMRGRDDTAA---IRISNLSESMTEADLEELVKKIGPQSKM 217
            .|:.|.....::...:|.:...:.|.:.:.|.::   |.:.:||..:....|.|.....|..|..
  Fly    60 TALTAMNKRLFLEKEIKVNWATSPGNQPKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNC 124

  Fly   218 YLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWS 264
            .:.||.:|...||:|:|.|.::.:|..||:.:||.......:...||
  Fly   125 RIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWS 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	10/48 (21%)
		RRM	<161..>269	CDD:223796	25/107 (23%)
		RRM_eIF3G_like	189..265	CDD:240854	22/79 (28%)
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	40/177 (23%)
		RRM1_TIA1_like	9..80	CDD:240798	16/84 (19%)
		RRM2_TIA1_like	96..170	CDD:240799	20/73 (27%)
		RRM3_TIA1_like	221..294	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910