DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and tia1

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_012814227.2	Gene:	tia1 / 394890	XenbaseID:	XB-GENE-1002876	Length:	389	Species:	Xenopus tropicalis

Alignment Length:	189	Identity:	43/189 - (22%)
Similarity:	73/189 - (38%)	Gaps:	33/189 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 VSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNMMEKKASAAAA 155
            |:|.:|:|..:.....|:...::|...|...|.:                   ...|.:.:||:.
Frog    18 VTEPLILQVFSQLGPCKSCKMIMDTAGNDPYCFV-------------------EFFEHRHAAASL 63

  Fly   156 AAVDAPK-SGKYV-------PPFLK---DSQKGALGMRGRDDTAAIRISNLSESMTEADLEELVK 209
            ||::..| .||.|       |...|   :|......:|.:|. ..:.:.:||..:|..|::....
Frog    64 AAMNGRKIMGKEVKVNWATTPSSQKKDANSSSVVSTLRSQDH-FHVFVGDLSPEITTDDIKAAFA 127

  Fly   210 KIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWS--KP 266
            ..|..|...:.:|..||..||:.:|.|..:.||..||..:.|.......:...|:  ||
Frog   128 PFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKP 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	8/48 (17%)
		RRM	<161..>269	CDD:223796	30/119 (25%)
		RRM_eIF3G_like	189..265	CDD:240854	19/77 (25%)
tia1	XP_012814227.2	RRM1_TIA1	8..81	CDD:410027	17/81 (21%)
		RRM2_TIA1	104..181	CDD:410030	19/77 (25%)
		RRM3_TIAR	214..286	CDD:241064
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910