DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and hnrnpa0b

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_999871.1	Gene:	hnrnpa0b / 334222	ZFINID:	ZDB-GENE-030131-6154	Length:	314	Species:	Danio rerio

Alignment Length:	171	Identity:	42/171 - (24%)
Similarity:	69/171 - (40%)	Gaps:	19/171 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 EEIIMQFLNSKEDEKANDPL---LDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNMMEKKASAAA 154
            |::...|:.....:..||.|   .:...|:..|.:...:....:..:......|:.....|.||.
Zfish     5 EKLCKLFVGGLNVQTTNDGLRSYFEQFGNLTDCVVVQNDQLQRSRCFGFVTYSTSEEADAAMAAR 69

  Fly   155 AAAVDAPKSGKYVPPFLKDSQKGALGMRGRDDTAA----IRISNLSESMTEADLEELVKKIGPQS 215
            ...||    ||.|......:::.|    ||.:..|    |.:..|.:.:.|.||.|...:.|...
Zfish    70 PHVVD----GKNVEVKRAVAREDA----GRPEALAKVKKIFVGGLKDDIEEKDLTEFFSQFGMIE 126

  Fly   216 KMYLARDKNTGLCKGFAYVHFKQRKDAAAAI----EILNGH 252
            |..:..||:||..:||.:|||:....|..|:    .::|||
Zfish   127 KSEVITDKDTGKKRGFGFVHFEDNDSADKAVVLKFHMINGH 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	7/49 (14%)
		RRM	<161..>269	CDD:223796	29/100 (29%)
		RRM_eIF3G_like	189..265	CDD:240854	23/72 (32%)
hnrnpa0b	NP_999871.1	RRM1_hnRNPA0	6..84	CDD:240772	15/81 (19%)
		RRM_SF	100..179	CDD:302621	22/68 (32%)
		HnRNPA1	263..294	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910