DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and Celf5

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001361632.1	Gene:	Celf5 / 319586	MGIID:	2442333	Length:	446	Species:	Mus musculus

Alignment Length:	135	Identity:	33/135 - (24%)
Similarity:	55/135 - (40%)	Gaps:	17/135 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 YKGTAMDTNMMEKKASAAAAAAVDAPKSGKYVPPFLKDSQKGALGMRGRDDTAAIRISNLSESMT 200
            :.|....|.|....|.|..|.:|..|      |..|:..::|..|..       :.|.:|.:...
Mouse   322 FSGVQQYTAMYPTAAIAPVAHSVPQP------PHLLQQQREGPEGCN-------LFIYHLPQEFG 373

  Fly   201 EADLEELVKKIGP--QSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEW 263
            :.:|.::....|.  .||:::.|..|...|  |.:|.|.....|.|||:.:||.......|.|:.
Mouse   374 DTELTQMFLPFGNIISSKVFMDRATNQSKC--FGFVSFDHPASAQAAIQAMNGFQIGMKRLKVQL 436

  Fly   264 SKPQN 268
            .:|::
Mouse   437 KRPKD 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	1/3 (33%)
		RRM	<161..>269	CDD:223796	26/110 (24%)
		RRM_eIF3G_like	189..265	CDD:240854	20/77 (26%)
Celf5	NP_001361632.1	RRM1_CELF3_4_5_6	2..88	CDD:241076
		PABP-1234	<9..358	CDD:130689	10/41 (24%)
		RRM2_CELF3_4_5_6	95..175	CDD:241079
		RRM3_CELF3_4_5_6	357..435	CDD:241083	21/86 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910