DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF3g1 and tcg1

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_595090.2	Gene:	tcg1 / 2541062	PomBaseID:	SPBC660.11	Length:	349	Species:	Schizosaccharomyces pombe

Alignment Length:	277	Identity:	64/277 - (23%)
Similarity:	108/277 - (38%)	Gaps:	52/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ADEVELDYGGLPPTTETVENGQKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVA-----KRRTW 71
            ||:..:..|.|..:|:..|....:.|   .....|.|...|..:...::||..:|     .:...
pombe    42 ADDFRVFVGRLSTSTKKSEIRSLFET---VGTVRKVTIPFRRVRRGTRLVPSGIAFVTFNNQEDV 103

  Fly    72 TKFGDSKNDKPGPNSQTTMVSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPY 136
            .|..::.|.|       |:...||::|        ||......|.|:..|.:..|||.     |.
pombe   104 DKAIETLNGK-------TLDDREIVVQ--------KARPVQEQPIKDRKKSKNKNGEE-----PE 148

  Fly   137 KGTAMDTNMMEKKASA--AAAAAVDAPKSGKYVPPFLKDSQKGALGMRGRDDTA-----AIRISN 194
            ..|::: |....|.|:  ..|....||.|.:......|.::....|..|::...     :|.:|.
pombe   149 TSTSVE-NAESAKGSSDENEANTATAPSSNEANGVDKKQNEIKGKGGSGKNKAKPLPPNSIYVSG 212

  Fly   195 LSESMTEADLEEL------------VKKIGPQ--SKMYLARDKNTGLCKGFAYVHFKQRKDAAAA 245
            ||.::|...|:|:            |:.:.|.  .::.|..::..|  :||.:|.|...:|.:.|
pombe   213 LSVTLTNEGLKEMFDAYNPTRARIAVRSLPPYIIRRIKLRGEQRRG--RGFGFVSFANAEDQSRA 275

  Fly   246 IEILNGHGYDHLILSVE 262
            ||.:||.....|.|.|:
pombe   276 IEEMNGKQVGDLTLVVK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	24/114 (21%)
		RRM	<161..>269	CDD:223796	29/121 (24%)
		RRM_eIF3G_like	189..265	CDD:240854	24/88 (27%)
tcg1	NP_595090.2	RRM_SF	46..124	CDD:302621	18/95 (19%)
tcg1	NP_595090.2	RRM	207..291	CDD:214636	23/85 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910