DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and AgaP_AGAP009952

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_319085.4	Gene:	AgaP_AGAP009952 / 1279370	VectorBaseID:	AGAP009952	Length:	363	Species:	Anopheles gambiae

Alignment Length:	231	Identity:	47/231 - (20%)
Similarity:	87/231 - (37%)	Gaps:	76/231 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 KDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGDSKN-----DKPG-----PNSQT--------- 88
            ::|.||.::..| :.:|:..:.:  |..::..|:.::     ||||     .::.|
Mosquito    22 QEDSKTNLIVNY-LPQQMTQEEI--RSLFSSIGEVESCKLIRDKPGCVTRHAHTHTYIHLFDGCY 83

  Fly    89 TMVSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNMMEKKASAA 153
            .:..:.:...|:|.:..|.|:..:                         .|.....:..|:...:
Mosquito    84 LLTGQSLGYGFVNYQRAEDASKAI-------------------------NTLNGLRLQNKQIKVS 123

  Fly   154 AAAAVDAPKSGKYVPPFLKDSQKGALGMRGRDDTAAIRISNLSESMTEADLEELVKKIGPQSKMY 218
                            |.:.|.:...|       |.:.:|.|.::|.:||||.|   ..|..::.
Mosquito   124 ----------------FARPSSEAIKG-------ANLYVSGLPKNMLQADLEAL---FSPYGRII 162

  Fly   219 LAR---DKNTGLCKGFAYVHFKQRKDAAAAIEILNG 251
            .:|   |..|||.||..::.|.||.:|..||:.|||
Mosquito   163 TSRILCDNITGLSKGVGFIRFDQRMEAEKAIKELNG 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	16/115 (14%)
		RRM	<161..>269	CDD:223796	29/94 (31%)
		RRM_eIF3G_like	189..265	CDD:240854	25/66 (38%)
AgaP_AGAP009952	XP_319085.4	ELAV_HUD_SF	24..361	CDD:273741	47/229 (21%)
		RRM1_Hu	26..125	CDD:241094	17/142 (12%)
		RRM2_Hu	135..213	CDD:241096	26/67 (39%)
		RRM3_Hu	279..356	CDD:240823
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910