DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and AgaP_AGAP002335

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_312633.5	Gene:	AgaP_AGAP002335 / 1273632	VectorBaseID:	AGAP002335	Length:	458	Species:	Anopheles gambiae

Alignment Length:	184	Identity:	39/184 - (21%)
Similarity:	72/184 - (39%)	Gaps:	30/184 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 TMVSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDT-NMMEKKASA 152
            |.|:||::.             .|......:..|:|           .:.|::|. ..:|.....
Mosquito    17 TSVTEELLC-------------TLFSQMGTVKSCKI-----------IRETSIDPFAFIEYANHQ 57

  Fly   153 AAAAAVDAPKSGKYVPPFLKDSQKGALGMRGRDDTAA---IRISNLSESMTEADLEELVKKIGPQ 214
            :|..|:.|.....::...::.:...:.|.:.:.||:.   |.:.:||..:....|.|.....|..
Mosquito    58 SAQTALAAMNKRMFLKKEIRVNWATSAGNQPKTDTSQHHHIFVGDLSPEIDTETLREAFAPFGEI 122

  Fly   215 SKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWS--KP 266
            |...:.||..|...:|:|:|.|.::.:|..||.::||.......:...||  ||
Mosquito   123 SNCRIVRDPQTLKSRGYAFVSFVKKAEAENAIAMMNGQWLGSRSIRTNWSTRKP 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	7/50 (14%)
		RRM	<161..>269	CDD:223796	26/111 (23%)
		RRM_eIF3G_like	189..265	CDD:240854	21/80 (26%)
AgaP_AGAP002335	XP_312633.5	RRM1_TIA1_like	10..81	CDD:240798	13/87 (15%)
		RRM2_TIA1_like	97..171	CDD:240799	19/73 (26%)
		RRM3_TIA1_like	206..279	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910