DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and AgaP_AGAP000965

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_309157.5	Gene:	AgaP_AGAP000965 / 1270460	VectorBaseID:	AGAP000965	Length:	340	Species:	Anopheles gambiae

Alignment Length:	255	Identity:	61/255 - (23%)
Similarity:	98/255 - (38%)	Gaps:	76/255 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ETV-ENGQKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVAK---RRTWTKFGDSKNDKPGPNSQ 87
            ||| :||:.  ......::|.||.::..|      :|:|:.:   :..::..||.::.|
Mosquito     7 ETVQQNGRS--GSIGSGQEDSKTNLIVNY------LPQTMTQEEVKSLFSSIGDVESCK------ 57

  Fly    88 TTMVSEEIIMQ-----FLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNMME 147
              ::.:::..|     |:|....|.|..                    ::| .:.|..:....:
Mosquito    58 --LIRDKVTGQSLGYGFVNYHRPEDAEK--------------------AIN-TFNGLRLQNKTI- 98

  Fly   148 KKASAAAAAAVDAPKSGKYVPPFLKDSQKGALGMRGRDDTAAIRISNLSESMTEADLEELVKKIG 212
             |.|.|      .|.|         |:.||          |.:.:|.||:|||:.|||.|....|
Mosquito    99 -KVSFA------RPSS---------DAIKG----------ANLYVSGLSKSMTQQDLENLFNAYG 137

  Fly   213 PQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNG---HGYDHLILSVEWSKPQNN 269
            ......:..|..|||.||..::.|.||.:|..||:.|||   .|....|.....:.|.||
Mosquito   138 QIITSRILCDNITGLSKGVGFIRFDQRSEAERAIQQLNGTTPKGASEPITVKFANNPSNN 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	18/117 (15%)
		RRM	<161..>269	CDD:223796	35/110 (32%)
		RRM_eIF3G_like	189..265	CDD:240854	28/78 (36%)
AgaP_AGAP000965	XP_309157.5	ELAV_HUD_SF	24..336	CDD:273741	56/236 (24%)
		RRM1_Hu	26..103	CDD:241094	17/113 (15%)
		RRM2_Hu	113..191	CDD:241096	29/77 (38%)
		RRM3_Hu	254..331	CDD:240823
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910