DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g1 and EIF3G_ANOGA

DIOPT Version :9

Sequence 1:	NP_570011.1	Gene:	eIF3g1 / 31243	FlyBaseID:	FBgn0029629	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_308202.3	Gene:	EIF3G_ANOGA / 1269559	VectorBaseID:	AGAP007668	Length:	271	Species:	Anopheles gambiae

Alignment Length:	271	Identity:	183/271 - (67%)
Similarity:	216/271 - (79%)	Gaps:	5/271 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPGVETIKSSWADEVELDYGGLPPTTETVENGQKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTV 65
            ||.::.||||||||||.|.|.|||.:|.:|||||.||||||||||||.|||||||||:.||||.|
Mosquito     1 MPALDDIKSSWADEVESDSGSLPPPSEVIENGQKIVTEYKYNKDDKKVKVVRTYKISRVVVPKCV 65

  Fly    66 AKRRTWTKFGDSKNDKPGPNSQTTMVSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHW 130
            |:|::..|||||..|:||||.|||||||::.|||:.:||:|:.|:..||..|||.|||.|.||||
Mosquito    66 ARRKSLAKFGDSATDRPGPNPQTTMVSEDVFMQFITNKEEEQKNENALDSMKNIVKCRTCEGEHW 130

  Fly   131 SVNCPYKGTAMDTNMMEKKASAAAAAAVDAPKSGKYVPPFLKDSQ-KGALG--MRGRDDTAAIRI 192
            |.:||||.:|.|  ...|..:|.......:.|.||||||.:|:|| |..:|  |||||||:||||
Mosquito   131 SFHCPYKNSAYD--KPTKPTTAPVPETTSSSKPGKYVPPHMKESQGKPGIGGAMRGRDDTSAIRI 193

  Fly   193 SNLSESMTEADLEELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHL 257
            |||||:||||||||||||.||.:||:|:|||:||||||||||||:.|:|||.|||:|||:|||||
Mosquito   194 SNLSEAMTEADLEELVKKFGPHTKMFLSRDKSTGLCKGFAYVHFRSRRDAATAIEVLNGYGYDHL 258

  Fly   258 ILSVEWSKPQN 268
            |||||||||||
Mosquito   259 ILSVEWSKPQN 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g1	NP_570011.1	eIF3g	30..140	CDD:289149	75/109 (69%)
		RRM	<161..>269	CDD:223796	86/111 (77%)
		RRM_eIF3G_like	189..265	CDD:240854	62/75 (83%)
EIF3G_ANOGA	XP_308202.3	eIF3g	30..137	CDD:289149	73/106 (69%)
		RRM	<185..>271	CDD:223796	71/85 (84%)
		RRM_eIF3G_like	190..266	CDD:240854	62/75 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	168	1.000	Domainoid score	I7897
eggNOG	1	0.900	-	-		E1_KOG0122
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2784
Inparanoid	1	1.050	376	1.000	Inparanoid score	I4220
OMA	1	1.010	-	-		QHG55427
OrthoDB	1	1.010	-	-		D1226059at2759
OrthoFinder	1	1.000	-	-		FOG0003558
OrthoInspector	1	1.000	-	-		oto108711
Panther	1	1.100	-	-	LDO	PTHR10352
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2433
TreeFam	1	0.960	-	-
	13	12.940