Protein Alignment Klp3A and ZCF125

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_564744.1
• Gene: ZCF125 / 842245
• AraportID: AT1G59540
• Length: 823
• Species: Arabidopsis thaliana
• Alignment Length: 1049
• Identity: 261/1049 - (24%)
• Similarity: 433/1049 - (41%)
• Gaps: 295/1049 - (28%)

  Fly     9 VAVALRVRPLVQSELDRGC--------RIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLF 65
            :.||:||||...   :.|.        ||::.:|.| .|..|.    |:.:::|||...:...::
plant     4 ICVAVRVRPPAP---ENGASLWKVEDNRISLHKSLD-TPITTA----SHAFDHVFDESSTNASVY 60

  Fly    66 ETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHVGVIPRAVHDIFTAIAEMQSE 130
            |...:..:...:.|:|.|..|||||.||||:||..:     :...|:|.|:|.|:|..| .|.|:
plant    61 ELLTKDIIHAAVEGFNGTAFAYGQTSSGKTFTMTGS-----ETDPGIIRRSVRDVFERI-HMISD 119

  Fly   131 FRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIRE-VKNRIIMPGLTELVVTSAQQVTDHLIRGS 194
            ..|.:..|::|:|.|:..||.:.:.:   .:.|.| ::..:.:.||.|.:|:.|:|:...:..|.
plant   120 REFLIRVSYMEIYNEEINDLLAVENQ---RLQIHEHLERGVFVAGLKEEIVSDAEQILKLIDSGE 181

  Fly   195 AGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQS--VTTSRFNLVDLAGSERCSKTLASGDRFK 257
            ..|....|.||..|||||.||.:.:.:...|...|  :..|..||||||||||.:||.|.|.|.:
plant   182 VNRHFGETNMNVHSSRSHTIFRMVIESRGKDNSSSDAIRVSVLNLVDLAGSERIAKTGAGGVRLQ 246

  Fly   258 EGVNINKGLLALGNVINALG-SGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAE 321
            ||..|||.|:.||||||.|. |.:...:||||.|||||:||.:||||:.|.:|..::|.::::.|
plant   247 EGKYINKSLMILGNVINKLSDSTKLRAHIPYRDSKLTRILQPALGGNAKTCIICTIAPEEHHIEE 311

  Fly   322 TLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISAVGAAGLGAI 386
            :..||::|.||.:|.|         .|:||           |:|:
plant   312 SKGTLQFASRAKRITN---------CAQVN-----------EILT-------------------- 336

  Fly   387 PCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQ----QELHQSLLDLTEKEMRAHIAEQAHDKL 447
                       :||.::|.|.::..|:   .|||    :.|.|.:|:|:.:.::   .|...::|
plant   337 -----------DAALLKRQKLEIEELR---MKLQGSHAEVLEQEILNLSNQMLK---YELECERL 384

  Fly   448 RSHVSELKNKLDQRE------QAQFGNEN---TNGD---NEMRDFSLLVNRVHVELQRTQEELES 500
            ::.:.|.|.|..::|      |.:..|.|   ||.|   |:..|| ::..:....|....:..:.
plant   385 KTQLEEEKRKQKEQENCIKEQQMKIENLNNFVTNSDFKRNQSEDF-IISRKTPDGLCNVNDTSDV 448

  Fly   501 QG-----HESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQEL 560
            .|     ..||..:.:||:...|.|   :...|:||..
plant   449 PGTPCFKSASRSFVVARSNNYSGLS---DFSPMVHSLG--------------------------- 483

  Fly   561 HERIMRNFSRLDSDDEDVKLRLCNQKIDDLEAERRDLMDQLR---NIKSKDISAKLA-------- 614
                       |..|||..::|....:.||        ||::   .:|.:.....:|
plant   484 -----------DVADEDTWMKLNKGFVADL--------DQIQFTPAVKCQPTPLSIATTECPREN 529

  Fly   615 ----EERRKRLQLLEQEISDLRRKLITQA----NLLKIRDKEREKIQNLSTEIRTMKESKVKLIR 671
                |:.:.|:|||..|...|:.|...|.    ||:       :::..|..|..|:||...:|
plant   530 HSEVEDLKSRIQLLTNENDSLQVKFNEQVLLSNNLM-------QEMSELKQETLTVKEIPNRL-- 585

  Fly   672 AMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDA 736
                 ||.....|.|.:..:..:||.....:|...                  ..|.....:..:
plant   586 -----SESVANCKDVYKDVIVTMKSLITDKESPTA------------------NLLLGTTEITTS 627

  Fly   737 LERQASAQAQRHKYKDNGGSAAGSSNANAKTDSW----VDRELEIILSLIDAEHSLEQLMEDRAV 797
            |  .|:.:.|.....|  |...|||..:..:|.|    |:.:....|.|.||:...|       .
plant   628 L--LATLETQFSMIMD--GQKTGSSIDHPLSDHWETLRVNLKNTTTLLLSDAQAKDE-------F 681

  Fly   798 INNHYHLLQQEKTSDPAEAAEQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQS 862
            :|:|      .|..:.|...|:     .|:.||.:...:.::|::::|   ||.         |.
plant   682 LNSH------NKGQETAALEEK-----KLKSELIIIKERYNELEKELC---LDK---------QL 723

  Fly   863 LGESRTVSKQLLKTLVQQRRLQASSLNEQRTTLDELRAQLLDAQQQEDAASKRLRLLQSQHEEQM 927
            |..||...::|:|        :...|.|:|.:||...:|          :::|||::.|..|..:
plant   724 LEASRESHEKLIK--------EVQFLKEERDSLDRKISQ----------STQRLRVIASDKENAL 770

  Fly   928 ------LAQQRAYEEK---VSVLIRTANQRWAEARSPAEDQQRNQILEELLSSREALQQELDKLR 983
                  :.:::..||:   :|:...|.:                   :..:|....::.::.||.
plant   771 KDLNVEVKRRKDMEEEIKHISIAFATRH-------------------KSFVSFHSEIKSKMQKLT 816

  Fly   984 AKNKSKSKA 992
            .:|   |||
plant   817 TQN---SKA 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	124/338 (37%)
		Smc	<453..>985	CDD:440809	112/580 (19%)
		Metallothio	<1071..1115	CDD:395080
ZCF125	NP_564744.1	KISc_CENP_E	3..325	CDD:276825	124/337 (37%)
		Cortex-I_coil	711..787	CDD:312712	23/105 (22%)