Protein Alignment Klp3A and HIK

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_173273.2
• Gene: HIK / 838418
• AraportID: AT1G18370
• Length: 974
• Species: Arabidopsis thaliana
• Alignment Length: 1158
• Identity: 271/1158 - (23%)
• Similarity: 471/1158 - (40%)
• Gaps: 322/1158 - (27%)

  Fly     9 VAVALRVRPLVQSELDRGCRIAVERSAD----GAPQV--TVNRNESYTYNYVFDIDDSQKDLFET 67
            :.|.:|:||:.:.||....::|.|...|    ..|||  .::...|:|::.||..:...::::|.
plant    32 IVVTVRLRPMNKRELLAKDQVAWECVNDHTIVSKPQVQERLHHQSSFTFDKVFGPESLTENVYED 96

  Fly    68 CVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHVGVIPRAVHDIFTAIAEMQSEFR 132
            .|:......|.|.|.||.|||||.|||||||.           ||..:||:||:..|.: ..|..
plant    97 GVKNVALSALMGINATIFAYGQTSSGKTYTMR-----------GVTEKAVNDIYNHIIK-TPERD 149

  Fly   133 FAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNRIIMPGLTELVVTSAQQVTDHLIR-GSAG 196
            |.:..|.:|:|.|...||.:|.: .:|...:.:.:...::..|.|....:...:. |||. ..|.
plant   150 FTIKISGLEIYNENVRDLLNSDS-GRALKLLDDPEKGTVVEKLVEETANNDNHLR-HLISICEAQ 212

  Fly   197 RAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTT--SRFNLVDLAGSERCSKTLASGDRFKEG 259
            |.|..||:|:||||||.|..||:.:|..:....|.:  :..|.||||||||.|::.|.|.|.:||
plant   213 RQVGETALNDTSSRSHQIIRLTIQSTHRENSDCVRSYMASLNFVDLAGSERASQSQADGTRLREG 277

  Fly   260 VNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETLS 324
            .:||..|:.|..||..|..|:.:|:||||.|||||:||.|||||:.|.:|..:|||..:|.::.:
plant   278 CHINLSLMTLTTVIRKLSVGKRSGHIPYRDSKLTRILQHSLGGNARTAIICTLSPALAHVEQSRN 342

  Fly   325 TLRYADRALQIKNKPVVNLDPHAAEVNML---KDVIQKLRVELLSGGKMSSSLISAVGAAGLGAI 386
            ||.:|:||.::.|.         |.|||:   |.:::.|:
plant   343 TLYFANRAKEVTNN---------AHVNMVVSDKQLVKHLQ------------------------- 373

  Fly   387 PCEESLAGSMANAAEIQRLKEQVRT---LQDRNRKLQQELHQSLLDLTEKEMRAHIAEQAHDKLR 448
                         .|:.||:.:.||   ..:::.|:||      :::...|:|     :..|..:
plant   374 -------------KEVARLEAERRTPGPSTEKDFKIQQ------MEMEIGELR-----RQRDDAQ 414

  Fly   449 SHVSELKNKLDQREQAQFG-NENTNGDNEMR---DFSLLV--NRVHVELQRTQEELESQGHESRQ 507
            ..:.||:.||...:|...| |...:.|..:|   .:|:.|  :..:..|.|.:...::...:|..
plant   415 IQLEELRQKLQGDQQQNKGLNPFESPDPPVRKCLSYSVAVTPSSENKTLNRNERARKTTMRQSMI 479

  Fly   508 RLSSRS-----HTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQEL--HERIM 565
            |.||.:     |         |:.::  .|.:|...::...|.|:        |::|:  |
plant   480 RQSSTAPFTLMH---------EIRKL--EHLQEQLGEEATKALEV--------LQKEVACH---- 521

  Fly   566 RNFSRLDSDDEDVKLRLCNQKIDDLEAERRDLMDQLRNIK--------------SKDISAKLAEE 616
                ||.:.|       ..|.|..|:||.|    ::|.:|              :|.:||.|.||
plant   522 ----RLGNQD-------AAQTIAKLQAEIR----EMRTVKPSAMLKEVGDVIAPNKSVSANLKEE 571

  Fly   617 RRKRLQLLEQEISDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFR 681
                               ||:.:      .:...|.||..::.::::|..||:.::...
plant   572 -------------------ITRLH------SQGSTIANLEEQLESVQKSIDKLVMSLPSN----- 606

  Fly   682 QWKMVREKELTQLKSKDRKMQSEIVRQQTL----HSKQRQVLKRKCEEALAANKRLKDALERQAS 742
                :...:.|. |:|:...||:..:...|    .|.::..||..| ..|:|::::.|
plant   607 ----ISAGDETP-KTKNHHHQSKKKKLLPLTPSSASNRQNFLKSPC-SPLSASRQVLD------- 658

  Fly   743 AQAQRHKYKDNGGSAA-GSSNANAKTDSWVDRELEIILSLIDAEHSLEQLMEDRAVINNHYHLLQ 806
            ..|:....::|..||| |::....                  :|....|..|:...:::......
plant   659 CDAENKAPQENNSSAARGATTPQG------------------SEKETPQKGEESGDVSSREGTPG 705

  Fly   807 QEKTSDPAEAAEQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSK 871
            ..::|.......|.....:.||.:....|.:::|:::|....                    ..|
plant   706 YRRSSSVNMKKMQQMFQNAAEENVRSIRAYVTELKERVAKLQ--------------------YQK 750

  Fly   872 QLLKTLVQQRRLQA------SSLNEQRTTLDELRAQLLDAQQQEDA-----ASKRLRLLQSQH-- 923
            |||  :.|...|:|      |..||:.|.::       |.:|.:.|     ..:|.::::..|
plant   751 QLL--VCQVLELEANDGAGYSVENEENTIME-------DEEQNQVAWHITFIEERQQIIELWHVC 806

  Fly   924 EEQMLAQQRAY-------EEKVSVLIRTANQRWAEAR-------SPAEDQQRNQILEELLSSREA 974
            ...::.:.:.|       .:::.:.:......|.|..       :||.:...:.:  .|.||.:|
plant   807 HVSIIHRTQFYLLFKGDQADQIYMEVELRRLTWLEQHLAEVGNATPARNCDESVV--SLSSSIKA 869

  Fly   975 LQQELDKLRAKNKSKSKAVKSE--PQDLDDSFQIVDGNETVVLSDVSDDPDWVPSTSKSKRIQ-- 1035
            |::|.:.|       :|.|.|.  |::.::.:...|                ||...|.:::|
plant   870 LRREREFL-------AKRVNSRLTPEEREELYMKWD----------------VPLEGKQRKLQFV 911

  Fly  1036 -------SDSRNVISPPEKQDANVTS-------LGNSSIQSLNSTSATEDGKR 1074
                   .|||:|     ::.|.:.:       .||.|.:......|....||
plant   912 NKLWTDPYDSRHV-----QESAEIVAKLVGFCESGNISKEMFELNFAVPSDKR 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	125/335 (37%)
		Smc	<453..>985	CDD:440809	108/590 (18%)
		Metallothio	<1071..1115	CDD:395080	2/4 (50%)
HIK	NP_173273.2	KISc_CENP_E	31..353	CDD:276825	125/334 (37%)
		COG4913	<467..>599	CDD:443941	36/194 (19%)
		DUF3490	791..955	CDD:463424	32/193 (17%)