Protein Alignment Klp3A and PAKRP1

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_567423.1
• Gene: PAKRP1 / 827054
• AraportID: AT4G14150
• Length: 1292
• Species: Arabidopsis thaliana
• Alignment Length: 1242
• Identity: 325/1242 - (26%)
• Similarity: 528/1242 - (42%)
• Gaps: 250/1242 - (20%)

  Fly     7 SCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLFETCVQA 71
            |.|.|.:|::||.:.|  .|..|..:.|.|   .:||: .:::|::.:.:.:.:|:.:|:.....
plant    90 SGVKVIVRMKPLNKGE--EGDMIVEKMSKD---SLTVS-GQTFTFDSIANPESTQEQMFQLVGAP 148

  Fly    72 KVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHV-----GVIPRAVHDIFTAIAEMQ--- 128
            .|:..|:|:|.::.|||||||||||||....||:|::|:     |:.||....:|..|.|.|
plant   149 LVENCLSGFNSSVFAYGQTGSGKTYTMWGPANGLLEEHLCGDQRGLTPRVFERLFARIKEEQVKH 213

  Fly   129 --SEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIRE-VKNRIIMPGLTELVVTSAQQVTDHL 190
              .:..:...||.:|:|.||..||.....::   :.||| ||:.:.:..|||..|.:...|:..|
plant   214 AERQLNYQCRCSLLEIYNEQITDLLDPSQKN---LMIREDVKSGVYVENLTEEYVKNLTDVSQLL 275

  Fly   191 IRGSAGRAVAATAMNETSSRSHAIFTLTLVA---TKLDGKQSVTTSRFNLVDLAGSERCSKTLAS 252
            |:|...|...||::|..|||||.:||..:.:   ...||..|..|||.||||||||||...|.|:
plant   276 IKGLGNRRTGATSVNTESSRSHCVFTCVVESRCKNVADGLSSFKTSRINLVDLAGSERQKSTGAA 340

  Fly   253 GDRFKEGVNINKGLLALGNVINALGSGQAAG---YIPYRQSKLTRLLQDSLGGNSITLMIACVSP 314
            |:|.||..|||:.|..|||:||.|......|   :||||.|:||.|||:|||||:...|:..|||
plant   341 GERLKEAGNINRSLSQLGNLINILAEISQTGKPRHIPYRDSRLTFLLQESLGGNAKLAMVCAVSP 405

  Fly   315 ADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLS------------- 366
            :....:||.||||:|.||..|:||.||| :....:||.|:.||.:||.||..
plant   406 SQSCRSETFSTLRFAQRAKAIQNKAVVN-EVMQDDVNFLRGVIHQLRDELQRMKNDGNNPTNPNV 469

  Fly   367 ------GGKMSSSLISAVGAAGLGAIPCEESLAGSM---ANAAEIQRLKEQVRTLQ--------- 413
                  ..:.|.:|:.:.|.....::|.|:: .|.:   .:.|.::||..|| .||
plant   470 AYSTAWNARRSLNLLRSFGLGHPRSLPHEDN-DGDIEMEIDEAAVERLCVQV-GLQSSLASEGIN 532

  Fly   414 -DRNRKLQQELHQSLLDLTEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNEM 477
             |.||  .:.:|.|.....||.: ...::.|.:....|.       :..|.....|..|..:..:
plant   533 HDMNR--VKSIHSSDGQSIEKRL-PEDSDVAMEDACCHT-------ENHEPETVDNMRTETETGI 587

  Fly   478 RDFSLLVNRVHVELQRTQEELESQGHESRQRL-SSRSHTEGGES------------------GGD 523
            |:     |::....|....|...|....:..| ||.:.:|...|                  |.|
plant   588 RE-----NQIKTHSQTLDHESSFQPLSVKDALCSSLNKSEDVSSCPDLVPQDVTSANVLIADGVD 647

  Fly   524 EVHEMLHSHSEE-----------YTNKQMNFAGELRNINRQLDLKQELHERIMRNFSRLDSDDED 577
            :...:::|.|..           ..:..::.:..:||..:.|...:      :...|:.||:.|:
plant   648 DPEHLVNSASPSLCIDPVGATPVLKSPTLSVSPTIRNSRKSLKTSE------LSTASQKDSEGEN 706

  Fly   578 VKLRLCNQKIDDLEAERRDL---MDQLRNIKSKDI---SAKLAEERRKRLQLLEQEISDLRRKLI 636
                |..:..|...|..:.:   ...|...|||..   :.:||....|.::|||.......::..
plant   707 ----LVTEAADPSPATSKKMNNCSSALSTQKSKVFPVRTERLASSLHKGIKLLESYCQSTAQRRS 767

  Fly   637 TQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRK- 700
            |.....|..|.|.      ||.| :..::.|:.|......||:       ..||....|.|.|:
plant   768 TYRFSFKAPDSEP------STSI-SKADAGVQTIPGADAISEE-------NTKEFLCCKCKCREQ 818

  Fly   701 -----------MQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDALERQASAQA--------- 745
                       :|...|....:..|.:..:.:..|:.||.:.|.:.|||...:.||
plant   819 FDAQQMGDMPNLQLVPVDNSEVAEKSKNQVPKAVEKVLAGSIRREMALEEFCTKQASEITQLNRL 883

  Fly   746 -QRHKYKDNGGSAAGSSNANAKTDSWVDRELEIIL--SLIDAEHSLEQLMEDRAVINNHYHLLQQ 807
             |::|::....:..|.:           ||.:||.  ||:|...|.|..:::......|.|.|.:
plant   884 VQQYKHERECNAIIGQT-----------REDKIIRLESLMDGVLSKEDFLDEEFASLLHEHKLLK 937

  Fly   808 EKTSDPAEAAEQARILASLEEELE-MRN------------AQISDLQ-QKVCPTD--LDSRIRSL 856
            :...:..|..:....|...:||:| .:|            .:|.||: |..|..|  |.|.:::.
plant   938 DMYQNHPEVLKTKIELERTQEEVENFKNFYGDMGEREVLLEEIQDLKLQLQCYIDPSLKSALKTC 1002

  Fly   857 --------AEGVQSLGESRTVSKQLLKTLVQQR------RLQASSLNEQ-RTTLDELRAQLLDAQ 906
                    |..|.::.||:  .:.|.|||.|:|      ..:..||:|: ||.|:..:| |::.|
plant  1003 TLLKLSYQAPPVNAIPESQ--DESLEKTLEQERLCWTEAETKWISLSEELRTELEASKA-LINKQ 1064

  Fly   907 QQEDAASKR----------------LRLLQ-----SQHEEQMLAQQRAYEEKVSVLIRTANQ--- 947
            :.|....||                .|:|:     .:...|:||:.|..::.:..:.:.|.:
plant  1065 KHELEIEKRCGEELKEAMQMAMEGHARMLEQYADLEEKHMQLLARHRRIQDGIDDVKKAAARAGV 1129

  Fly   948 RWAEARSPAEDQQRNQILEELLSSREALQQELDKLRAKNKSKSKAVKSEPQDLDDSFQIVDGNET 1012
            |.||:|          .:..|.:...||:.|.:|.|...:.::|:::::.:|..::.|.. |...
plant  1130 RGAESR----------FINALAAEISALKVEKEKERQYLRDENKSLQTQLRDTAEAIQAA-GELL 1183

  Fly  1013 VVLSDVSDDPDWVPSTSKSKRIQSDSRNVISPPEKQDANVTSLGNSSIQSLNSTSATEDGKRCKG 1077
            |.|.:..:.     .|...||.. |:....:...:|...:.....:.|.:||..........
plant  1184 VRLKEAEEG-----LTVAQKRAM-DAEYEAAEAYRQIDKLKKKHENEINTLNQLVPQSHIHN--- 1239

  Fly  1078 CKCRTKC 1084
             :|.|||
plant  1240 -ECSTKC 1245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	137/345 (40%)
		Smc	<453..>985	CDD:440809	133/646 (21%)
		Metallothio	<1071..1115	CDD:395080	4/14 (29%)
PAKRP1	NP_567423.1	PLN03188	2..1292	CDD:215621	325/1242 (26%)