Protein Alignment Klp3A and MRH2

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_001326426.1
• Gene: MRH2 / 824652
• AraportID: AT3G54870
• Length: 1051
• Species: Arabidopsis thaliana
• Alignment Length: 1088
• Identity: 285/1088 - (26%)
• Similarity: 466/1088 - (42%)
• Gaps: 236/1088 - (21%)

  Fly     5 DPSCVAVALRVRPLVQSEL--DRGCRIAVERSADGAPQVTVNRN----ESYTYNYVFDIDDSQKD 63
            ||..|.|::||||....||  |......||...: ..::.:.:|    |||.::.||....|||.
plant   101 DPGRVRVSVRVRPRNGEELISDADFADLVELQPE-IKRLKLRKNNWNSESYKFDEVFTDTASQKR 164

  Fly    64 LFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHV--GVIPRAVHDIFTAIAE 126
            ::|...:..|:.:|:|||.||:||||||:|||||:|....   ||..  |::.||:.||..
plant   165 VYEGVAKPVVEGVLSGYNGTIMAYGQTGTGKTYTVGKIGK---DDAAERGIMVRALEDILL---- 222

  Fly   127 MQSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIRE--VKNRIIMPGLTELVVTSAQQVTDH 189
            ..|....:|..|:::||.|...||.:.   :|..:.|.|  ....:.:||.|   |.:.|.: ||
plant   223 NASSASISVEISYLQLYMETIQDLLAP---EKNNISINEDAKTGEVSVPGAT---VVNIQDL-DH 280

  Fly   190 LIR----GSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQS--------------VTTSRFN 236
            .::    |...|..|.|.||..|||||||.|: .|...::.|..              |..|:..
plant   281 FLQVLQVGETNRHAANTKMNTESSRSHAILTV-YVRRAMNEKTEKAKPESLGDKAIPRVRKSKLL 344

  Fly   237 LVDLAGSERCSKTLASGDRFKEGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLG 301
            :||||||||.:|:...|...:|...||..|.:||..||||..|  :.:||.|.|||||||:||.|
plant   345 IVDLAGSERINKSGTDGHMIEEAKFINLSLTSLGKCINALAEG--SSHIPTRDSKLTRLLRDSFG 407

  Fly   302 GNSITLMIACVSPADYNVAETLSTLRYADRALQIKN---------------KPVVNLDPHAAEV- 350
            |::.|.:|..:.|:....|||.||:.:..||::|.|               |....:|...|||
plant   408 GSARTSLIITIGPSARYHAETTSTIMFGQRAMKIVNMVKLKEEFDYESLCRKLETQVDHLTAEVE 472

  Fly   351 --NMLK-----DVIQKLRVELLSGGKMSSSLISAVGAAGLGAIPCEESLAGSMANAAEIQRLKEQ 408
              |.|:     ::.::||                         .||.|.|.:..||  :.|.|
plant   473 RQNKLRNSEKHELEKRLR-------------------------ECENSFAEAEKNA--VTRSK-- 508

  Fly   409 VRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNG 473
              .|:..|.:|:..:.:.|.||   :::....:..|||    ..:|:.||...:|.|.  ||:..
plant   509 --FLEKENTRLELSMKELLKDL---QLQKDQCDLMHDK----AIQLEMKLKNTKQQQL--ENSAY 562

  Fly   474 DNEMRDFSLLVNRVHVEL-QRTQEE-----------LESQGHESRQRLSSRSHTEGGESGGDEVH 526
            :.::.|.|.:..:...|| ||.::|           .|.:...|:|:.|.....:|......|:.
plant   563 EAKLADTSQVYEKKIAELVQRVEDEQARSTNAEHQLTEMKNILSKQQKSIHEQEKGNYQYQRELA 627

  Fly   527 EMLHSHSEEYTNKQMNFAGELRNINRQLDLKQELHERIMRNFSRLDSD--------DEDVKLRLC 583
            |..|::..:....|....||        :.:....|..:|...||.||        :|..:|::
plant   628 ETTHTYESKIAELQKKLEGE--------NARSNAAEDQLRQMKRLISDRQVISQENEEANELKI- 683

  Fly   584 NQKIDDLEAERRDLMDQLRNIKSKDISAKLAEERRKRLQLLEQEISDLRRKLITQANLLKIRDKE 648
              |:::|.......:|:|:.:| .|....|.::.:     |.:|:.|::.:|:       :.:|:
plant   684 --KLEELSQMYESTVDELQTVK-LDYDDLLQQKEK-----LGEEVRDMKERLL-------LEEKQ 733

  Fly   649 REKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIVRQQTLH- 712
            |:::           ||::..::....|||...:.|...:::|:: .|.:...|:...|.|.|.
plant   734 RKQM-----------ESELSKLKKNLRESENVVEEKRYMKEDLSK-GSAESGAQTGSQRSQGLKK 786

  Fly   713 --SKQRQVLKRKCEEALAANKRLK----DALERQ----------ASAQAQRHKYKDNGGSAAGSS 761
              |.||..:.|.||| :...|.|:    :.||.|          |:.:|.:.|..:.||..|...
plant   787 SLSGQRATMARLCEE-VGIQKILQLIKSEDLEVQIQAVKVVANLAAEEANQVKIVEEGGVEALLM 850

  Fly   762 NANAKTDSWVDRELEIILSLIDAEHSLEQLMEDRAVINNHYHLLQQ--EKTSDPAEAAEQARILA 824
            ...:..:|.:.|    :.|...|..::.:..:|..:......||.:  .||.||......|..||
plant   851 LVQSSQNSTILR----VASGAIANLAMNEKSQDLIMNKGGAQLLAKMVTKTDDPQTLRMVAGALA 911

  Fly   825 SL---EEELEMRNAQ--ISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSKQLLKTLVQQRRLQ 884
            :|   |:.|::...:  |..|.......::|. |..:|.|:.:..:..|      :.::|.||..
plant   912 NLCGNEKFLKLLKEEEGIKGLLTMAQSGNIDI-IAQVARGMANFAKCET------REIMQGRRKG 969

  Fly   885 ASSLNEQRTTLDELRAQLLDAQQQEDAASKRLRLLQSQHEEQMLAQQRAYEEKVSVLIRTANQRW 949
            .|.|      |:|...:.|.:....|:||.:      :|.|..|......||.
plant   970 RSLL------LEEGVLEWLTSNSHIDSASTQ------RHIELALCHLAQNEEN------------ 1010

  Fly   950 AEARSPAEDQQRNQILEELLSSREALQQELDKLRAKNKSKSKAVKSEP 997
                  |.|.:|...:.|::  |.:::...|.:|:..|   |.:|:.|
plant  1011 ------ANDFKRTGSVTEIV--RISVESSRDDIRSLAK---KILKTNP 1047

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	128/356 (36%)
		Smc	<453..>985	CDD:440809	123/575 (21%)
		Metallothio	<1071..1115	CDD:395080
MRH2	NP_001326426.1	KISc	121..439	CDD:276812	119/335 (36%)
		Smc	<476..>757	CDD:440809	71/355 (20%)
		SRP1	718..>914	CDD:227396	49/219 (22%)
		armadillo repeat	804..829	CDD:293788	5/24 (21%)
		armadillo repeat	836..873	CDD:293788	8/40 (20%)
		Arm	839..873	CDD:425727	7/37 (19%)
		armadillo repeat	878..913	CDD:293788	10/34 (29%)