Protein Alignment Klp3A and KICP-02

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_566931.1
• Gene: KICP-02 / 824186
• AraportID: AT3G50240
• Length: 1051
• Species: Arabidopsis thaliana
• Alignment Length: 1165
• Identity: 344/1165 - (29%)
• Similarity: 529/1165 - (45%)
• Gaps: 276/1165 - (23%)

  Fly     2 SSEDPS-------CVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDD 59
            ||..||       ||.||:.||||:..|:.:|||..|..| ...|||.:. ...:|:::|:..:.
plant    12 SSSPPSSLSSESCCVKVAVNVRPLIGDEVTQGCRECVSVS-PVTPQVQMG-THPFTFDHVYGSNG 74

  Fly    60 SQKDL-FETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLD-DHVGVIPRAVHDIFT 122
            |...| ||.||...|..|.:|||.|:||||||||||||||||   |:.| ...|:||:.:..:|.
plant    75 SPSSLMFEECVAPLVDGLFHGYNATVLAYGQTGSGKTYTMGT---GIKDGTKNGLIPQVMSALFN 136

  Fly   123 AIAEMQSEFRFAVTCSFVELYQEQFYDLFSSK--------------TRDKATVDIREVKNRII-M 172
            .|..::.:..|.:..||:|:.:|:..||..|.              ...|:.|.|||..|.:| :
plant   137 KIDSVKHQMGFQLHVSFIEILKEEVLDLLDSSVPFNRLANGTPGKVVLSKSPVQIRESPNGVITL 201

  Fly   173 PGLTELVVTSAQQVTDHLIRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVT------ 231
            .|.||:.:.:.:::...|.:||..||..:|.||..|||||||||:||...:.....||.
plant   202 SGATEVPIATKEEMASCLEQGSLTRATGSTNMNNESSRSHAIFTITLEQMRKISSISVVKDTVDE 266

  Fly   232 -------TSRFNLVDLAGSERCSKTLASGDRFKEGVNINKGLLALGNVINALGS---GQAAGYIP 286
                   .::.:|||||||||..:|.:.|.|.|||::||:|||||||||:|||.   .:...::|
plant   267 DMGEEYCCAKLHLVDLAGSERAKRTGSGGVRLKEGIHINRGLLALGNVISALGDEKRRKEGAHVP 331

  Fly   287 YRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVN 351
            ||.|||||||||||||||.|:||||:||||.|..|||:||:||:||..|:||||.|.|...:|:.
plant   332 YRDSKLTRLLQDSLGGNSKTVMIACISPADINAEETLNTLKYANRARNIQNKPVANKDLICSEMQ 396

  Fly   352 MLKDVIQKLRVELLSGGKMSSSLISAVGAAGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRN 416
            .::..:|.|:..|.:.|..||.                           |:|.::|::..|:..|
plant   397 KMRQELQYLQATLCARGATSSE---------------------------EVQVMREKIMKLESAN 434

  Fly   417 RKLQQELH-----QSLLDLTEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNE 476
            .:|.:|||     :..||.      .:|..|....:.|....||.          |.|:.:.|.|
plant   435 EELSRELHIYRSKRVTLDY------CNIDAQEDGVIFSKDDGLKR----------GFESMDSDYE 483

  Fly   477 MRDFSLLVNRVHVELQRTQEELESQGHESRQRLSSRSHTEGGESGGDEVHEMLHSHSE-EYTNKQ 540
            |.:                                      ..|||  :.|.:.:..| |:..:|
plant   484 MSE--------------------------------------ATSGG--ISEDIGAAEEWEHALRQ 508

  Fly   541 MNFAGELRNINRQLDLKQELHERIMRNFSRLDSDDEDVKLRLC-----------NQKIDDLEAER 594
            .:...||..::::|:.|:.                   ::|:|           .:|:.:||.|:
plant   509 NSMGKELNELSKRLEEKES-------------------EMRVCGIGTETIRQHFEKKMMELEKEK 554

  Fly   595 RDLMDQ----LRNIK----SKDISAKLAEERR-KRLQLLEQEISDLRRKLITQANLLKIRDKERE 650
            |.:.|:    |..::    |.|..|::|.:.. .:|:.||.:|.:|::|...|..:||.:.|..:
plant   555 RTVQDERDMLLAEVEELAASSDRQAQVARDNHAHKLKALETQILNLKKKQENQVEVLKQKQKSED 619

  Fly   651 KIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIVRQQTLHSKQ 715
            ..:.|.|||:.:|..||:|.:.|:.|:|:|||||..:||||.|||.:.||.:.|.::.:.|:.:|
plant   620 AAKRLKTEIQCIKAQKVQLQQKMKQEAEQFRQWKASQEKELLQLKKEGRKTEHERLKLEALNRRQ 684

  Fly   716 RQVLKRKCEEALAANKRLKDALERQASAQAQRHKYKDNGGSAAGSSNANAKT-DSWVDRELEIIL 779
            :.||:||.|||..|.||||:.||.:.|:.   |...........|...|.|: ..|:|.|||::.
plant   685 KMVLQRKTEEAAMATKRLKELLEARKSSP---HDISVIANGQPPSRQTNEKSLRKWLDNELEVMA 746

  Fly   780 SLIDAEHSLEQLMEDRAVI---------------NNHYHLLQQEKTSDPAEAAEQARI--LASLE 827
            .:.......|:.::.||.:               |:|     |||.......:...|:  :||||
plant   747 KVHQVRFQYEKQIQVRAALAVELTSLRQEMEFPSNSH-----QEKNGQFRFLSPNTRLERIASLE 806

  Fly   828 EELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLG--------ESRTVSKQLLKTLVQQRRLQ 884
            ..|::.:..:         |.:.|::....|...||.        :|.|.:|.||:.:.......
plant   807 SMLDVSSNAL---------TAMGSQLSEAEEREHSLHAKPRWNHIQSMTDAKYLLQYVFDSTAEA 862

  Fly   885 ASSLNEQRTTLDELRAQLLDAQQQEDAASKRLRLLQ--SQHEEQMLAQQRAYEEKVSVLIRTANQ 947
            .|.:.|:...:.|.:.||.|.          |.|||  .....::|.:::..|:.||:.:.:.:.
plant   863 RSKIWEKDRDIKEKKEQLNDL----------LCLLQLTEVQNREILKEKKTREQTVSIALASTSS 917

  Fly   948 RWA-----------------EARSPAEDQQRNQ---------ILEELLSSREALQQELDKLRAKN 986
            .::                 :..||:....|..         |:...:...|||.:|..|::|..
plant   918 SYSGSSRSSSKHYGDNNASDDPSSPSSTYHRATKHLKYTGPGIVNISVRESEALLEETRKMKAMK 982

  Fly   987 K--SKSKAVK----------------SEPQDLDDSFQIVDGNETVVLS----DVSDDPDW 1024
            |  ...|..|                .:|..|.:..:..|.....|:|    |..||..|
plant   983 KMGQSGKLWKWKRSHHQWLLQFKWKWQKPWKLSEWIKQNDETTMHVMSKSHHDDEDDHSW 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	160/368 (43%)
		Smc	<453..>985	CDD:440809	140/606 (23%)
		Metallothio	<1071..1115	CDD:395080
KICP-02	NP_566931.1	KISc_KIF4	24..381	CDD:276823	159/361 (44%)
		PTZ00121	<418..906	CDD:173412	142/616 (23%)
		DUF5401	<520..>743	CDD:375164	75/244 (31%)