Protein Alignment Klp3A and POK1

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_001326049.1
• Gene: POK1 / 820999
• AraportID: AT3G17360
• Length: 2075
• Species: Arabidopsis thaliana
• Alignment Length: 1243
• Identity: 317/1243 - (25%)
• Similarity: 503/1243 - (40%)
• Gaps: 320/1243 - (25%)

  Fly     9 VAVALRVRPLVQSELDRGCRIAVERSADG--------APQVTV---NRNESYTYNYVFDIDDSQK 62
            |.|.:|:|||.          .:||:..|        :||..|   :....:|:::|.....||:
plant   169 VQVLIRLRPLG----------TMERANQGYGKCLKQESPQTLVWLGHPEARFTFDHVASETISQE 223

  Fly    63 DLFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMG---TAFNGVLDDHVGVIPRAVHDIFTAI 124
            .||.......|:..|:|||..:.|||||||||||||.   :...|.|.:..||..|....:|:.|
plant   224 KLFRVAGLPMVENCLSGYNSCVFAYGQTGSGKTYTMMGEISEAEGSLGEDCGVTARIFEYLFSRI 288

  Fly   125 AEMQSE------FRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIRE-VKNRIIMPGLTELVVTS 182
             :|:.|      .:|:..|||:|:|.||..||....:   ..:.:|| :...:.:..|.|..|.:
plant   289 -KMEEEERRDENLKFSCKCSFLEIYNEQITDLLEPSS---TNLQLREDLGKGVYVENLVEHNVRT 349

  Fly   183 AQQVTDHLIRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTTSRF---NLVDLAGSE 244
            ...|...|::|:..|.:|||.||..|||||::||.|:  ..|..|.|:|.|||   |||||||||
plant   350 VSDVLKLLLQGATNRKIAATRMNSESSRSHSVFTCTI--ESLWEKDSLTRSRFARLNLVDLAGSE 412

  Fly   245 RCSKTLASGDRFKEGVNINKGLLALGNVINA---LGSGQAAGYIPYRQSKLTRLLQDSLGGNSIT 306
            |...:.|.|||.||..||||.|..||.||.:   |..|:.. ::|||.|:||.||||||||||.|
plant   413 RQKSSGAEGDRLKEAANINKSLSTLGLVIMSLVDLAHGKHR-HVPYRDSRLTFLLQDSLGGNSKT 476

  Fly   307 LMIACVSPADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMS 371
            ::||.|||:..:..||||||::|.||..|:|...||.|. :.:|..|:..|:||:|:|.|..|..
plant   477 MIIANVSPSLCSTNETLSTLKFAQRAKLIQNNAKVNEDA-SGDVTALQQEIRKLKVQLTSLLKNH 540

  Fly   372 SSLISAVGAAGLGAI-PCEESL-----AGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDL 430
            .|         .||: .|..||     :|:...|.|         |.||:.....:.::.:::..
plant   541 DS---------CGALSDCISSLEESRYSGTCKVAGE---------TRQDKCHCQVKNMNDNMIGA 587

  Fly   431 TEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQ 495
            ..:|   .|||.|..|..:.:..:                   |..:||......|:.:.|...:
plant   588 LRRE---KIAESALQKSEAEIERI-------------------DCLVRDMEEDAKRIKIMLNLRE 630

  Fly   496 EELESQGHESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQEL 560
            |::              ...|...||.....|.|   .||  ||.:.  ||::.:...:|...||
plant   631 EKV--------------GEMEFCTSGSLMTKECL---IEE--NKTLK--GEIKLLRDSIDKNPEL 674

  Fly   561 HERIMRNFSRLDSDDEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKDISAKLAEERRKRLQLLE 625
            ....:          |:.|||                 :||:..:      |..|...:  :.|.
plant   675 TRSAL----------ENTKLR-----------------EQLQRYQ------KFYEHGER--EALL 704

  Fly   626 QEISDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKE 690
            .|::.||.:|:   ::|:.:|:...|        ..|||::      |..|.|..|.......:|
plant   705 AEVTGLRDQLL---DVLEAKDESFSK--------HVMKENE------MEKEFEDCRNMNSSLIRE 752

  Fly   691 LTQLKS------KDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRL-----KDALERQASAQ 744
            |.::::      ...::||.:|...|          |..|:...|:|.|     ....|.|....
plant   753 LDEIQAGLGRYLNFDQIQSNVVASST----------RGAEQVNQAHKHLMAETMPTISEIQEEVA 807

  Fly   745 AQRHKYKDNGGSAAGSSNANAKTDSWVDRELEIILSLIDAEHSLEQLM---EDRAVINNHY---- 802
            ....|..|.|        |..|||..:||.:        .:..|.:||   |:...:|..|
plant   808 ISHSKNYDRG--------ALVKTDEGIDRSI--------LQFKLGKLMKDLEEARTLNCKYEKDH 856

  Fly   803 --HLLQQEKTSDPAE--AAEQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSL 863
              .|.|||......|  ..|.||.:..|:||:   .|..|:.|:::|
plant   857 KSQLSQQEDIEVVREQVETETARTILELQEEV---IALQSEFQRRIC------------------ 900

  Fly   864 GESRTVSKQLLKTLVQQRRLQASSLNE--QRTTLDELRAQLLDAQQQEDAASKRLRLLQS----- 921
              :.|...|.:|..:..|..:..:||:  ::.||:.....:..::..::|:::...::.|
plant   901 --NLTEENQSIKDTITARESEIRALNQDWEKATLELTNFIVAGSKSIKNASTQIESIICSFPQVN 963

  Fly   922 ---------------QHEEQMLAQQRAYEEKVSVLIRTANQRWAEARSPAEDQQRNQILEELLSS 971
                           :.||.:|..|::.|: ..:|:...|.:....:.........|:.....::
plant   964 AWIGDYVEKAAKNCIKKEETILLLQKSLED-ARILVAEMNLKLNSLKGATIALNEFQLGGNAATT 1027

  Fly   972 REA---------LQQELDKLRAKNKSKSKAVKSEPQDLDDSFQIVDGNETVVLSDVSDDPDWVPS 1027
            .||         :..|:|.|.:..|:...::....:..:.:..:     |..|||..|....:
plant  1028 EEAFNLNNDVDRMSDEVDTLESNFKANQYSILKTERHAEAALAV-----TKWLSDSRDQHQMM-- 1085

  Fly  1028 TSKSKRIQSDSRNVISPPEKQDANVTSLGNSSIQSLN----------------STSATEDGKRCK 1076
                :::|..|...........|::::.||:.| ||:                |||:: |...|:
plant  1086 ----EKVQDQSVKEFGTLSSISASLSAEGNADI-SLSRDGHLSDATYPKGDELSTSSS-DFSNCR 1144

  Fly  1077 ---GCKCRTKC----TTKRCGCLSGNNACSETCVCKSNCRNPLNLKDHASQCGDGDGQ------- 1127
               .|....||    :::.....|.|...|...:.|       |...|:..||:|...
plant  1145 WQHDCALNVKCQGVSSSESDAQESNNKITSAALIAK-------NGSAHSVYCGEGRQSVEKPLTI 1202

  Fly  1128 ---KDETE 1132
               ::|||
plant  1203 MMGREETE 1210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	142/353 (40%)
		Smc	<453..>985	CDD:440809	109/584 (19%)
		Metallothio	<1071..1115	CDD:395080	10/50 (20%)
POK1	NP_001326049.1	KISc_KLP2_like	167..514	CDD:276824	146/361 (40%)
		PLN03188	<564..>714	CDD:215621	43/236 (18%)
		SMC_N	<587..>879	CDD:481474	83/412 (20%)
		CCDC158	1271..>1994	CDD:464943
		SMC_prok_B	<1490..1818	CDD:274008