Protein Alignment Klp3A and AT3G12020

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_001189866.1
• Gene: AT3G12020 / 820376
• AraportID: AT3G12020
• Length: 1044
• Species: Arabidopsis thaliana
• Alignment Length: 1148
• Identity: 289/1148 - (25%)
• Similarity: 461/1148 - (40%)
• Gaps: 345/1148 - (30%)

  Fly     9 VAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNE-----SYTYNYVFDIDDSQKDLFETC 68
            |.|.:|.|||...|:.:|..:|  ..|||.   |:.|||     :|.|:.||....:.:::::..
plant    70 VTVTVRFRPLSPREIRQGEEVA--WYADGE---TIVRNEHNPTIAYAYDRVFGPTTTTRNVYDIA 129

  Fly    69 VQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDH-----VGVIPRAVHDIFTAIAEMQ 128
            ....|...:.|.|.||.|||.|.||||:||          |     .|:||.||.|.|:.|.|..
plant   130 AHHVVNGAMEGINGTIFAYGVTSSGKTHTM----------HGDQRSPGIIPLAVKDAFSIIQETP 184

  Fly   129 SEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNRIIMPGLTELVVTSAQQVTDHLIRG 193
            :. .|.:..|::|:|.|...||.:....:   :.|||.|....:.|:.|.||.|.......:..|
plant   185 NR-EFLLRISYMEIYNEVVNDLLNPAGHN---LRIREDKQGTFVEGIKEEVVLSPAHALSLIAAG 245

  Fly   194 SAGRAVAATAMNETSSRSHAIFTLTLVATKLDGK---QSVTTSRFNLVDLAGSERCSKTLASGDR 255
            ...|.|.:|..|..|||||.|||||:.::.|..|   ::|..|:.||||||||| .||...||.|
plant   246 EEQRHVGSTNFNLLSSRSHTIFTLTIESSPLGDKSKGEAVHLSQLNLVDLAGSE-SSKVETSGVR 309

  Fly   256 FKEGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVA 320
            .|||..|||.||.||.||:.| :...|.::|||.|||||:||.||.|:....:|..|:||..:..
plant   310 RKEGSYINKSLLTLGTVISKL-TDVRASHVPYRDSKLTRILQSSLSGHDRVSLICTVTPASSSSE 373

  Fly   321 ETLSTLRYADRA----LQIKNKPVVN----LDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISA 377
            ||.:||::|.||    :|.:...:::    :..:..|:..||:.:::|:.|::
plant   374 ETHNTLKFAHRAKHIEIQAEQNKIIDEKSLIKKYQREIRQLKEELEQLKQEIV------------ 426

  Fly   378 VGAAGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAE- 441
                   .:|..:.:     .|.:|..||::   |:|...|||..|.:      |:|.:|.:..
plant   427 -------PVPQLKDI-----GADDIVLLKQK---LEDGQVKLQSRLEE------EEEAKAALLSR 470

  Fly   442 -QAHDKL------RSHVSELKNKLDQREQAQFGNE----------------------NTNGDNEM 477
             |...||      ....|.|.::.:.|.:..||.|                      :..|::|:
plant   471 IQRLTKLILVSTKNPQASRLPHRFNPRRRHSFGEEELAYLPYKRRDMMDDEQLDLYVSVEGNHEI 535

  Fly   478 RDFSLLVNRVHVELQRTQEELESQGH--------ESRQRLSSRS--------------------- 513
            ||            ...:||.:::.|        :.|...||.|
plant   536 RD------------NAYREEKKTRKHGLLNWLKPKKRDHSSSASDQSSVVKSNSTPSTPQGGGSH 588

  Fly   514 -HTEGGESGGDEVHEMLHSHSE-----EYTNKQMNFAGELRNINRQLDLKQELHERIMRNFSRLD 572
             |||...|.|..:.|.|....|     |.::.:|........::.:|||.:| .::|:
plant   589 LHTESRLSEGSPLMEQLSEPREDREALEDSSHEMEIPETSNKMSDELDLLRE-QKKIL------- 645

  Fly   573 SDDEDVKLRLCNQKIDDLEA----ERRDLMDQLRNIKSKDISAKLAEERRKRLQLLEQEISD--- 630
              .|:..|:|.:.|....||    :..::.:::: :.:.||.||     ..::..||::|.|
plant   646 --SEEAALQLSSLKRMSDEAAKSPQNEEINEEIK-VLNDDIKAK-----NDQIATLERQIMDFVM 702

  Fly   631 -----LRRKLITQANLLKIRDKEREKIQNLS--------------TEIR---------------- 660
                 |.:..|.|| :.::||:..||...|.              .|:|
plant   703 TSHEALDKSDIMQA-VAELRDQLNEKSFELEVIELFLFMQFFFIYAEVRDGFAIAWIRLFILAQY 766

  Fly   661 -----TMKESKVKLIRAMRGESEKFRQWKMV-------REKELTQLKSKDRKMQSEIVRQQTLHS 713
                 ..|.|.|.:|:....:.:.....|::       ......|:|:.|.:     :.||||:.
plant   767 YLSSYLNKVSSVYIIKYQYSKRQTILTMKLMVCSTLFSHSSSCLQVKAADNR-----IIQQTLNE 826

  Fly   714 K--QRQVLKRKCEEALAANKRLKDALERQASAQAQRHKYKDNGGSAAGSSNANAKTDSWVDRELE 776
            |  :.:||:   ||.....::|.:|||     .||..|.|
plant   827 KTCECEVLQ---EEVANLKQQLSEALE-----LAQGTKIK------------------------- 858

  Fly   777 IILSLIDAEHSLEQLMEDRAVINNHYHLLQQEKTSDPAEAAEQARILASLEEELEMRNAQISDLQ 841
                                                  |..:.|:.|:..:|:||:||.::::..
plant   859 --------------------------------------ELKQDAKELSESKEQLELRNRKLAEES 885

  Fly   842 QKVCPTDLDSRIRSLAEGVQSLG--ESRTVSKQLLKTLVQQRRLQA---------SSLNEQRTTL 895
                         |.|:|:.|..  |.:.:|:::.|.:.|..||.|         :..|:..||.
plant   886 -------------SYAKGLASAAAVELKALSEEVAKLMNQNERLAAELATQKSPIAQRNKTGTTT 937

  Fly   896 ---DELRAQLLDAQQQEDAASKRLRLLQSQHEEQMLAQQRAYEEKVSVLIRTANQRWAE-ARSPA 956
               :..|.:.|..:|:.|:.|..|:......:|:.|:.:.|..||        .||.|| .|...
plant   938 NVRNNGRRESLAKRQEHDSPSMELKRELRMSKERELSYEAALGEK--------EQREAELERILE 994

  Fly   957 EDQQRNQILEELLSSREALQQELDKLRAKNKSKSKAVKSEPQD 999
            |.:||...||..|::...|   :.|||     :|:...||..|
plant   995 ETKQREAYLENELANMWVL---VSKLR-----RSQGADSEISD 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	133/343 (39%)
		Smc	<453..>985	CDD:440809	129/659 (20%)
		Metallothio	<1071..1115	CDD:395080
AT3G12020	NP_001189866.1	KISc_CENP_E	69..388	CDD:276825	132/338 (39%)
		SMC_prok_B	<372..>1041	CDD:274008	164/825 (20%)