Protein Alignment Klp3A and AT2G21380

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_565510.1
• Gene: AT2G21380 / 816676
• AraportID: AT2G21380
• Length: 1058
• Species: Arabidopsis thaliana
• Alignment Length: 1186
• Identity: 290/1186 - (24%)
• Similarity: 497/1186 - (41%)
• Gaps: 304/1186 - (25%)

  Fly     1 MSSEDPSCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLF 65
            ::||..| ::|.:|.||:.:.|..||..|.....||...:...|...:|.::.||....:..:::
plant    98 ITSERDS-ISVTVRFRPMSEREYQRGDEIVWYPDADKMVRNEYNPLTAYAFDKVFGPQSTTPEVY 161

  Fly    66 ETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHVGVIPRAVHDIFTAIAEMQSE 130
            :...:..||..:.|.|.|:.|||.|.||||:||    :|. .|..|:||.|:.|:|:.|.|....
plant   162 DVAAKPVVKAAMEGVNGTVFAYGVTSSGKTHTM----HGD-QDFPGIIPLAIKDVFSIIQETTGR 221

  Fly   131 FRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNRIIMPGLTELVVTSAQQVTDHLIRGSA 195
             .|.:..|::|:|.|...||.....::   :.|||......:.|:.|.||.|.......:..|..
plant   222 -EFLLRVSYLEIYNEVINDLLDPTGQN---LRIREDSQGTYVEGIKEEVVLSPGHALSFIAAGEE 282

  Fly   196 GRAVAATAMNETSSRSHAIFTLTLVATKLDGKQ--SVTTSRFNLVDLAGSERCSKTLASGDRFKE 258
            .|.|.:...|..|||||.|||| ::.:...|.|  .|..|:.||:|||||| .|||..:|.|.||
plant   283 HRHVGSNNFNLMSSRSHTIFTL-MIESSAHGDQYDGVIFSQLNLIDLAGSE-SSKTETTGLRRKE 345

  Fly   259 GVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETL 323
            |..|||.||.||.||..|..|:.. ::|:|.||||||||.||.|:....:|..|:||..:..||.
plant   346 GAYINKSLLTLGTVIGKLTEGKTT-HVPFRDSKLTRLLQSSLSGHGHVSLICTVTPASSSTEETH 409

  Fly   324 STLRYADRALQI-----KNKPVVN---LDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISAVGA 380
            :||::|.||.:|     :||.:..   :..:..|::.||..:.:||..:|.|
plant   410 NTLKFASRAKRIEINASRNKIIDEKSLIKKYQKEISTLKVELDQLRRGVLVG------------- 461

  Fly   381 AGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAEQAHD 445
                 :..||.|:           ||:|   ||:...|:|..|.:.              |:|..
plant   462 -----VSHEELLS-----------LKQQ---LQEGQVKMQSRLEEE--------------EEAKA 493

  Fly   446 KLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELESQGHESRQRLS 510
            .|.|.:.:| .||                       :||:        |:..:  .|:.......
plant   494 ALMSRIQKL-TKL-----------------------ILVS--------TKNSI--PGYLGDTPAH 524

  Fly   511 SRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELR-------NINRQLDLKQELHERIMRNF 568
            |||.:.|.:...|.:  :|.|.:....:..::.|.:.|       :.|..:..:.||.:.:|..
plant   525 SRSISAGKDDKLDSL--LLDSDNLASPSSTLSLASDARRSSSKFKDENSPVGSRAELTQGVMTP- 586

  Fly   569 SRLDSDDEDVKL-------------RLCNQKIDDLEAERRDLMDQLRNIKSKDISAKLAEERRKR 620
            ..:|...|.||:             ||.:|.::|.|..:    .|::|::: ||     :|::::
plant   587 DEMDLLVEQVKMLAGEIAFGTSTLKRLVDQSMNDPENSK----TQIQNLEN-DI-----QEKQRQ 641

  Fly   621 LQLLEQEISDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKM 685
            ::.|||.|::.....|..|:.:::    :||:..|.|:... |..::::|.|
plant   642 MKSLEQRITESGEASIANASSIEM----QEKVMRLMTQCNE-KSFELEIISA------------- 688

  Fly   686 VREKELTQLKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKD---ALERQASAQAQR 747
                            .:.|:::|         |:.||.|    |..|.:   .||::.|:|
plant   689 ----------------DNRILQEQ---------LQTKCTE----NNELHEKVHLLEQRLSSQ--- 721

  Fly   748 HKYKDNGGSAAGSSNANAKTDSWVD------RELEIILSLIDAEHSLEQLMEDRAVINNHYHLLQ 806
                     .|..|..:..|:.:||      :..||....:..||  .|.:|:::.:.     :|
plant   722 ---------KATLSCCDVVTEEYVDELKKKVQSQEIENEKLKLEH--VQSVEEKSGLR-----VQ 770

  Fly   807 QEKTSDPAEAAEQARILASLE--------EELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSL 863
            .:|.::.|..|::....|::|        .:|.::||::.  ::.|...||.:..:.......:.
plant   771 NQKLAEEASYAKELASAAAIELKNLADEVTKLSLQNAKLE--KELVAARDLAAAAQKRNNNSMNS 833

  Fly   864 GESRTVSKQLLKTLVQQRRLQASSLNEQRTTLDELRAQLLDAQQQEDAASKRLRLLQSQHEEQML 928
            ..:|..::...|..:.    .:.:||::..|::      |.|::|.:|..           |..|
plant   834 AANRNGTRPGRKARIS----DSWNLNQENLTME------LQARKQREAVL-----------EAAL 877

  Fly   929 AQQRAYEEKVSVLIRTANQRWAEARSPAED-QQRNQILEELLSSREALQQELDKLRAKNKSKSKA 992
            |::...||              |.|..||: ::|.:.||..|::...|..:|.|..:...|..|:
plant   878 AEKEYIEE--------------EFRKKAEEAKRREEALENDLANMWVLVAKLKKANSGALSIQKS 928

  Fly   993 VKSEPQDLDD---------------SFQIVDGNETVVLSDVSDDPDWVPSTSKSK-RIQSDSRNV 1041
            .::||...|:               ..|:|:|:|.|:::...:.|...|..::.| |:|
plant   929 DEAEPAKEDEVTELDNKNEQNAILKERQLVNGHEEVIVAKAEETPKEEPLVARLKARMQ------ 987

  Fly  1042 ISPPEKQDANVTSLGNSSIQSLNSTSATEDGKRCKGC----------KCRTKCTTKRCGCLSGNN 1096
                |.::..:.|      |:..:.:|..:...||.|          .||..|..|.|..
plant   988 ----EMKEKEMKS------QAAAAANADANSHICKVCFESPTATILLPCRHFCLCKSCSL----- 1037

  Fly  1097 ACSETCVCKSNCRNPL 1112
            ||||..:|::...:.|
plant  1038 ACSECPICRTKISDRL 1053

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	124/335 (37%)
		Smc	<453..>985	CDD:440809	107/569 (19%)
		Metallothio	<1071..1115	CDD:395080	14/52 (27%)
AT2G21380	NP_565510.1	KISc_CENP_E	104..421	CDD:276825	123/329 (37%)
		Mplasa_alph_rch	<609..>813	CDD:275316	55/281 (20%)
		PTZ00121	<737..997	CDD:173412	61/319 (19%)
		mRING-HC-C3HC5_CGRF1-like	1009..1046	CDD:438311	12/41 (29%)