Protein Alignment Klp3A and si:dkey-26i13.8

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: XP_009304780.1
• Gene: si:dkey-26i13.8 / 797363
• ZFINID: ZDB-GENE-090312-134
• Length: 991
• Species: Danio rerio
• Alignment Length: 1230
• Identity: 287/1230 - (23%)
• Similarity: 496/1230 - (40%)
• Gaps: 361/1230 - (29%)

  Fly     9 VAVALRVRPLVQSELDRGCRIAVER-------------SADGAPQVTVNRNESYTYNYVFDIDDS 60
            :.||||:|||.::|::.|..|...:             .:|...:...:|.::|.::..||...:
Zfish    13 LTVALRIRPLNEAEIEEGATIVAHKIDNQMVVLMDPCEDSDNVLRAHRSREKTYMFDLAFDYTAT 77

  Fly    61 QKDLFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTM-GTAFNGVLDDHVGVIPRAVHDIFTAI 124
            |:|::....:..:..::.|||.|:.|||.||:|||:|| |      ||...|:..|.::|:|.||
Zfish    78 QEDVYVATTKNLIDGVIAGYNATVFAYGPTGAGKTHTMLG------LDSEPGIYIRTLNDLFRAI 136

  Fly   125 AEMQSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIRE-VKNRIIMPGLTELVVTSAQQVTD 188
            .:...:...:|..|::|:|.|...||.:..:   ..:::|| .|..|.:.|:||....:|:::..
Zfish   137 EDSTEDLDCSVYMSYIEIYNEMIRDLLNPSS---GYLELREDGKGEIRIAGITEFSTCNAKEIMA 198

  Fly   189 HLIRGSAGRAVAATAMNETSSRSHAIFTLTL--VATKLDGKQSVTTSRFNLVDLAGSERCSKTLA 251
            .|.:|:..|...:||.|:||||||||..:|:  .:...|..:.|...:..:|||||:||.|:|..
Zfish   199 LLTKGNKQRTQESTAANKTSSRSHAILQVTVKQKSRVKDINEEVRVGKLFMVDLAGTERASQTQN 263

  Fly   252 SGDRFKEGVNINKGLLALGNVINALG--SGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSP 314
            .|.|.|||.:||:.||||.|.||||.  .|:.|.::.||.|||||||:|:|||||.|:||..:||
Zfish   264 RGKRMKEGAHINRSLLALANCINALSEKGGKGAQFVNYRDSKLTRLLKDALGGNSRTVMITHISP 328

  Fly   315 ADYNVAETLSTLRYADRALQIKNK---PVVNLDPHAAE----VNMLKDVIQKLRVELLSGGKMSS 372
            |..|..|:.:||.|||:|..|:.|   .::|:..|.|:    :..|:..|::||.::   .:.|
Zfish   329 ASSNFEESRNTLVYADKAKNIRTKVKRNLMNVSYHLAQYTRIIADLRSEIERLRAKI---DQQS- 389

  Fly   373 SLISAVGAAGLGAIPCEESLAGSMAN----AAEIQRLKE-QVRTLQDR---NRKLQQELHQSLLD 429
                            ::.|.|..|:    .||:|:... ::..||::   ..:.|.|:.:||::
Zfish   390 ----------------QDQLKGEKADIRNIQAEVQQYSHGEMALLQEQLLSAFREQMEIRRSLME 438

  Fly   430 LTEKEMRAHIAEQAH---------DKLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVN 485
            |....|..||....|         |:.|:          :||:.:...:..:.|.|
Zfish   439 LENCNMELHIDTSRHLLTISDWERDRARA----------RREKDELSGQKKHTDKE--------- 484

  Fly   486 RVHVELQRTQEELESQGHESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNI 550
                      ||.||...|.:...::|          :|:..:|   :|:
Zfish   485 ----------EEQESMPEEPQYVTAAR----------EEIGPLL---AEQ--------------- 511

  Fly   551 NRQLDLKQELHERIMRNFSRLDSDDEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKDISAKLAE 615
            .:.::||:||.|:::             .::|.:.||::|      |..::.|.:.:||
Zfish   512 RKTMELKRELEEKLL-------------NMKLKSSKIEEL------LPKRISNTEQRDI------ 551

  Fly   616 ERRKRLQLLEQEISDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKF 680
                 |.|                 |.|:.:.|.||     |||::....|..::|
Zfish   552 -----LML-----------------LCKVHELELEK-----TEIQSAVLCKENVLR--------- 580

  Fly   681 RQWKMVREKELTQLKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDALERQASAQA 745
                           :||..:|.        |.:||.:    |::.:...|.|
Zfish   581 ---------------TKDFIIQR--------HEQQRTL----CDDIIHQQKML------------ 606

  Fly   746 QRHKYKDNGGSAAGSSNANAKTDSWVDRELEIILSLIDAEHS---LEQLMEDRAVINNHYHLLQQ 807
                .:|.|              ..|...|:.:.||...|.|   ::|::.......|:.:
Zfish   607 ----IEDQG--------------LCVPEGLQELYSLYFGELSDGIIDQILNLHTFTTNNLN---- 649

  Fly   808 EKTSDPAEAAEQAR--ILASLEE--ELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRT 868
                     |.|.|  ::::|||  :.|..|.:.|.|.:.  |.|      |.:.|:....::..
Zfish   650 ---------ARQLRLDVISNLEEADKAEQSNVKFSPLDKH--PRD------SSSSGLDYDSDTNR 697

  Fly   869 VSKQLLKTLVQQRRLQASSLNE------------------QRTTLDELRAQLLDAQQQEDAASKR 915
            |.|.|.|  ::.||...||.::                  :..:.|.||..:.|.:.....|:||
Zfish   698 VFKSLSK--IKPRRQHHSSSSQTLMRKVCAVKDSTPICPTESVSPDTLREIVSDTKSISVIAAKR 760

  Fly   916 LRLLQSQHEEQM--------LAQQRAYEEKVSVL------IRTANQRWAEARSPAEDQQRNQILE 966
            ...||::...:|        |....:.:..||.|      :|.::||...:....:|.:|.:
Zfish   761 RSRLQAKSNSRMAGMGLAAGLKSSVSMDSLVSTLPDESAEVRRSHQRHGGSSQSKQDPKRTE--- 822

  Fly   967 ELLSSREALQQELDKLRAKNKSKSKAVKSEPQDLDDSFQIVDGNETVVLSDVSDDPDWVPSTSKS 1031
               ...|..:::..|.|:::...||....:|:.        :.:....|..:||:....|:.:..
Zfish   823 ---GRTELPEKQQHKKRSRSFEASKRQVQKPRQ--------NASRYPALESISDNHLVRPALNII 876

  Fly  1032 KRIQSDSRNVISPP---------------EKQDANVTSLGNSSIQSLNS----TSATEDGKRCKG 1077
            :.:.....|..:||               :.|...:.....|:|...:|    ..|....:|.:|
Zfish   877 QPLNGGPANPATPPVAKVKIPVSHFTGEVQFQKLEIRGTPPSTIHQKHSDTKRAQAVYKRQRGQG 941

  Fly  1078 CKCRTKCTTKRCGCLSGNNACSETCVCKSNCRNPLNLKDHASQCGDGD-GQKDETEDADK 1136
            ..|......::.|...           ||...||       .|....| .:|:||...:|
Zfish   942 DVCYPSSLLQQAGNYK-----------KSTNENP-------KQKAMADVNRKNETRQRNK 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	128/345 (37%)
		Smc	<453..>985	CDD:440809	101/570 (18%)
		Metallothio	<1071..1115	CDD:395080	8/43 (19%)
si:dkey-26i13.8	XP_009304780.1	KISc_KIP3_like	12..349	CDD:276821	128/344 (37%)