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Protein Alignment Klp3A and KIFC1

DIOPT Version :10

Sequence 1:	NP_525053.1	Gene:	Klp3A / 31240	FlyBaseID:	FBgn0011606	Length:	1212	Species:	Drosophila melanogaster
Sequence 2:	XP_054187052.1	Gene:	KIFC1 / 3833	HGNCID:	6389	Length:	674	Species:	Homo sapiens

Alignment Length:	381	Identity:	137/381 - (35%)
Similarity:	199/381 - (52%)	Gaps:	75/381 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VAVALRVRPLVQSE-----------------LDRGCRIAVERSAD------GAPQVTVNRNESYT 50
            :.|..||||::..|                 .|...|:::.||.:      |||......:  ::
Human   311 IRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHD--FS 373

  Fly    51 YNYVFDIDDSQKDLFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTM--GTAFNGVLDDHVGVI 113
            ::.||.....|.::||. :...|:..|:||.|.|.||||||||||:||  |...:..|:   |:|
Human   374 FDRVFPPGSGQDEVFEE-IAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLE---GLI 434

  Fly   114 PRAVHDIFTAIAEMQSE-FRFAVTCSFVELYQEQFYDLFSSKTR--DKATVDIREVKNRIIMPGL 175
            |||:..:|:...|:..: :.::...|:||:|.|...||.::.||  .....:||...     ||.
Human   435 PRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAG-----PGS 494

  Fly   176 TELVVTSAQQV-------TD---HLIRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSV 230
            .||.||:|:.|       .|   ||.|  ..||||.||.||.|||||::|.|     ::.|:.|
Human   495 EELTVTNARYVPVSCEKEVDALLHLAR--QNRAVARTAQNERSSRSHSVFQL-----QISGEHS- 551

  Fly   231 TTSR-------FNLVDLAGSERCSKTLASG----DRFKEGVNINKGLLALGNVINALGSGQAAGY 284
              ||       .:|||||||||....||.|    :|.:|...||..|..||.||.||.:.::  :
Human   552 --SRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKES--H 612

  Fly   285 IPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETLSTLRYADRALQIKNKPV 340
            :|||.||||.|||:||||::..||...:||.:.||:|:|::||:|.:   ::..||
Human   613 VPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASK---VRLPPV 665

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.