Protein Alignment Klp3A and CG5004

DIOPT Version :9

• Sequence 1: NP_001284830.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Alignment Length: 1211
• Identity: 205/1211 - (16%)
• Similarity: 401/1211 - (33%)
• Gaps: 418/1211 - (34%)

  Fly   189 HLIRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQ------SVTTSRFNLVDLAGSERCS 247
            ||:....||...|..::........|.:....:..|:|..      ::..|..|.|.|. .|:.|
  Fly    18 HLVSLGGGRLSTAVTIHYIHIGDTTIGSAASCSISLNGSGVRPLHCTIYRSDANEVTLV-PEKDS 81

  Fly   248 KTLASGDRFKEGVNINKG-LLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIAC 311
            :.|..|....|...:::| ::.:||          :.|:.:......::::.::|.|.      .
  Fly    82 RLLIDGAPILEETKLSQGAMITIGN----------SNYLRFNNPDEAQMMRSAMGSNE------R 130

  Fly   312 VSPADYNVAETLSTLRYADRALQIKN------KPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKM 370
            :|....:..::........::|::::      .|:.|  |...|:...|              ..
  Fly   131 ISMPQIDFTQSARQAHELSQSLELESFYESIINPINN--PSTYELECPK--------------VF 179

  Fly   371 SSSLISAVGAAGLGAIPCEESLAGSMA----NAAEIQRLKEQVRTLQDR-------------NRK 418
            ||.|::.       .:|.::.|....|    |.||..|.::|:.....:             |..
  Fly   180 SSDLVTV-------NMPAKDVLGQKYASFARNLAENHRNEKQLNNQYAKGVGSNGGYWNVPSNAA 237

  Fly   419 LQQELHQSLLDLTEKEMRAHIAEQAHDK-----------LRSHVSELKNKLDQREQAQFGNENTN 472
            :.:|.||.......:::...:....:|:           :....|::.|     ..|...|..|.
  Fly   238 IYKEQHQQQHQQAPQDLLTKVNNDRYDRYPKAGGLQIYSMNGVNSDINN-----GPATGNNSGTG 297

  Fly   473 GDNEMRDF-----------------------------SLLVNRVHV--ELQRTQEE--------- 497
            |..|:.|.                             .::.||:..  .|.|.:.:
  Fly   298 GGAELEDMLKICTEYADRNNSMPSTHNVSSTSSITSSPIVQNRIKTNGSLPRDKNKSPFPQQAGV 362

  Fly   498 ---------LESQGHE-------SRQRLSSRSHT-----EGGESGG------------DEVHEML 529
                     ..|.|:|       :|..::.:.|.     :||.|.|            ...||.|
  Fly   363 ASSANISLLSSSSGYENVRLLGPNRVEINGQIHVPASAGDGGSSSGVSSNALAPTAAVRASHENL 427

  Fly   530 H-SHSE----EY----------TN-----KQMNF--------------AGELRNINRQLDL---- 556
            : :||.    :|          ||     |.::|              :..:.:.::.:.:
  Fly   428 NQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPPLASSAVVSTSKPIPIPSMV 492

  Fly   557 ------------KQELHERIMRNFSRLDSD-DEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKD 608
                        :|..:|::.::|.|.... |..|..:..|:.|::|....:.:..|.::.|.
  Fly   493 KPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRSNKNINNLTLNLQSVESQTQSPKP-- 555

  Fly   609 ISAKLAE-------ERRKRLQLLEQEISDLRRKLITQANL--------LKIRDKEREKIQNLSTE 658
             |.|.|.       |:|:|.:|:::. ..|:|:|   |.|        |:::..|:....:.|..
  Fly   556 -SRKPAPAPRSIHLEQRQRRELIQRR-KQLKREL---AELPPSAGIEGLELKLGEQPLAPSASPR 615

  Fly   659 IRTMK-ESKVKLIRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIVRQQTLHSKQRQVLKRK 722
            ::... :::|..:.|.|..:      :::.|.:..:||      ||..::|..| .|.|.:||:|
  Fly   616 LQLQALQNRVCRLEAQRNAT------RVMEENQQAKLK------QSIEIKQDQL-KKLRAMLKQK 667

  Fly   723 CEEALAANKRLKDALERQA-SAQAQRHKYKDNGGSAAGSSNANAKTDSWVDRELEIILSLIDAEH 786
            ...|.     ||:.|:... |.::.|..::|                      ||......::||
  Fly   668 PNNAC-----LKEELQLVCESLESDRKTFED----------------------LEFQYFEEESEH 705

  Fly   787 SLEQLMEDRAVINNHYHLLQQEKTSDPAEAAEQARILASLEEELEMRNAQIS-DLQQKVCPTDLD 850
            ..           :|....:||:           |::  ||.||.....||. |.::...||...
  Fly   706 HA-----------SHEEFKRQEQ-----------RLM--LEAELAALRIQIGPDEEEPGSPTSPG 746

  Fly   851 SRIRSLAEGV--QSL------------GESRTVSKQLLKTLVQQRRLQASSLNEQRTTL------ 895
            |...:|..||  |||            .:...:||.:.:.:....:::|::...:|..|
  Fly   747 STGSNLVNGVMSQSLFGSAELLCPKRRNQEDLMSKSVNENMFYNHKIEANTSTPKRLPLQLFEDL 811

  Fly   896 ----------------DELRAQLLDAQ--QQED-----------------AASKRL--RLLQSQH 923
                            |......|:.:  .|:|                 .||.::  .:::.:.
  Fly   812 AGGSCEQISFNLSLQGDRFEVNPLERRVPSQDDIDRSCKVANDAPISASQGASTKIFDSIMEIER 876

  Fly   924 EEQMLAQQRAYEEKVSVLIRTANQRWAEARSPAEDQQRNQILEELLSSREALQQ----ELDKLRA 984
            ..::|..|:.::     :|....|:..:.:..:.|:.|.|.   |||::::::|    |.|....
  Fly   877 NRKLLLAQQGHQ-----VIEHERQKMYDLKKKSHDEARTQY---LLSTQQSMEQQRQLESDANGG 933

  Fly   985 KN-----KSKSKAVKSEP-QDLDDSFQIVDGNETVVLSDVSDDPDWVPSTSKSKRIQSDSRNVIS 1043
            |:     |::.:.:..:| :.:||..|.:.|:                   |...:| :.::..|
  Fly   934 KDAKLFEKTELQKLNQKPGEPVDDQVQKIAGD-------------------KENNVQ-NRKSTGS 978

  Fly  1044 PPEKQDANVTSLGNSSIQSLNSTSATE--------DGKRCKGCKCRTKCTTKRCGCLSGNNACSE 1100
            .|.......|..|.:..|..:|....|        .|....|.....:...:....||..|.|..
  Fly   979 SPTTTTTTTTGGGTTPQQQRHSQPELEHHAIALGIGGGGSGGAGGANQMVARSPRPLSEANNCDA 1043

  Fly  1101 TC---------------VCKSNCRNPLNLKDHASQCGDGDG 1126
            |.               ....|.|...|.:|.|| .|.|.|
  Fly  1044 TIEAPKFANGMDSSASPAVADNKRASSNSQDTAS-AGSGSG 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_001284830.1	KISc_KIF4	7..336	CDD:276823	25/153 (16%)
		Kinesin	14..335	CDD:278646	25/152 (16%)
		Smc	<396..>994	CDD:224117	140/833 (17%)
		FlaC	522..633	CDD:225888	30/180 (17%)
		TCR	1075..1110	CDD:281618	7/49 (14%)
CG5004	NP_573195.1	FHA	41..104	CDD:278899	13/63 (21%)
		PH-like	1142..1242	CDD:302622
		PH	1143..1237	CDD:278594

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930