Protein Alignment Klp3A and Klp54D

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: XP_061516746.1
• Gene: Klp54D / 1280785
• VectorBaseID: AGAMI1_004503
• Length: 868
• Species: Anopheles gambiae
• Alignment Length: 807
• Identity: 203/807 - (25%)
• Similarity: 325/807 - (40%)
• Gaps: 204/807 - (25%)

  Fly     9 VAVALRVRPLVQSELDRGCRIAVERS------ADGAPQVT---VNRNESYTYNYVFDIDDSQKDL 64
            :.|.:|||||...|...|..:.|:..      .||.|..:   ..:.:.::||.||:...:|.|:
Mosquito   188 INVVVRVRPLSNKEARHGDEMVVQFPGNGQILCDGIPLTSGAGAQKPKLFSYNVVFEPGATQDDV 252

  Fly    65 FE-TCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNG-----------VLDDHVGVIPRAV 117
            .: :.::..::..:.|::.|...|||||||||:|:    .|           ..:|| |::.|:.
Mosquito   253 LQYSGIKRLIEMAIEGFSCTAFCYGQTGSGKTHTL----TGPPELFYRKPDPAHEDH-GLVFRSF 312

  Fly   118 HDIFTAIAEMQSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNRIIMPGLTELVVTS 182
            ..:|..:.| :.:..|.:..||:|:|.|:..||.:..|..|........|:|...  :..|....
Mosquito   313 LYLFKLLQE-RKDTNFVLKASFLEIYNEKVIDLLNPGTARKPLAVRWSKKSRGFF--VENLFTVD 374

  Fly   183 AQQVTDHLI---RGSAGRAVAATAMNETSSRSHAIFTLTLVA-TKLDGKQSVT-TSRFNLVDLAG 242
            .:::.|.|.   .|...|.|.:..||:.|||||.|.|:.:.: .:.:|...:: ..:.|.|||||
Mosquito   375 CEELDDLLAVLEEGMRNRHVGSHLMNDYSSRSHTILTVHITSEQQAEGGVFISKQGKINFVDLAG 439

  Fly   243 SERCSKTLASGDRFKEGVNINKGLLALGNVINALG-SGQAAGYIPYRQSKLTRLLQDSLGGNSIT 306
            ||...||.:.|...:|..||||.|:.||..|.:|. |.:..|:||||.||||:||.|||.||.:|
Mosquito   440 SEMTKKTHSEGKTLEEANNINKSLMVLGYCIASLSDSKRRGGHIPYRDSKLTKLLADSLAGNGVT 504

  Fly   307 LMIACVSPADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMS 371
            |||||:|||..||.||::|||||.||.:|:.||::.:||..|.:..||..|..|:||
Mosquito   505 LMIACISPAQSNVTETVNTLRYAARAKRIRTKPIIVMDPREALILSLKREIGALQVE-------- 561

  Fly   372 SSLISAVGAAGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMR 436
                             .|.|..::....|.|.:..||                   ||.|
Mosquito   562 -----------------NEHLRTALNLQTEAQDINSQV-------------------DLLE---- 586

  Fly   437 AHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELESQ 501
                       |..:.....|:|..:......      ||:::   ||.....|.|..::|
Mosquito   587 -----------RRPIPRSPPKVDVEKLTDMEG------NELKE---LVKVYVTENQALRQE---- 627

  Fly   502 GHESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQELHERIMR 566
                                          ::|.|:.::|        |.|..:|....:||:::
Mosquito   628 ------------------------------NAELYSTREM--------IIRDQELVCRENERLLK 654

  Fly   567 NFSRLDSDDEDVKLRLCNQKI------------------DDLEAE---RRDL---MDQLRNIKSK 607
            ..       |||....|...|                  .|||..   |..|   .|.:...:::
Mosquito   655 KL-------EDVNSVCCRSPIIPARPTFSAEMLNLSAASGDLEVSNIWRNPLSSSADSMNRYRNE 712

  Fly   608 DISAKLAEERRKRLQLLEQEISDLRR---KLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKL 669
            .:..:::....|..:||::|: |.||   .:.|.||.|...:......::..|.:..||
Mosquito   713 SLDGRVSANENKIPELLQKEL-DKRRIGDSITTIANNLTRNNSWDTANRSNGTSMHGMK------ 770

  Fly   670 IRAMRGESEKFRQWKMVREKELTQLKSKDRKMQSEIV-----RQQTLHSK--QRQVLKRKCEEAL 727
            :.:.:|.::.       |..:    .|:.|..|:.|:     ..||..|.  .....:|....:.
Mosquito   771 LASRKGSADS-------RHSD----PSQARTSQTRIIDLAPNPPQTARSSAASHPPWRRSAPRSS 824

  Fly   728 AANKRLKDALERQASAQAQRHKYKDNG 754
            :|.|.......|:.:....:.|..|.|
Mosquito   825 SAQKSATPLSVRKGTFLLAKSKSTDEG 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	123/353 (35%)
		Smc	<453..>985	CDD:440809	58/336 (17%)
		Metallothio	<1071..1115	CDD:395080
Klp54D	XP_061516746.1	None