Protein Alignment Klp3A and Klp64D

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: XP_312517.6
• Gene: Klp64D / 1273532
• VectorBaseID: AGAMI1_004514
• Length: 685
• Species: Anopheles gambiae
• Alignment Length: 651
• Identity: 222/651 - (34%)
• Similarity: 335/651 - (51%)
• Gaps: 71/651 - (10%)

  Fly     9 VAVALRVRPLVQSELDRGCR--IAVERSADGAPQVTVNRNES-----YTYNYVFDIDDSQKDLFE 66
            |.|.:||||:.:||||.|.:  |.|::|......|..|.|.|     |.::.||..|.:|.||:.
Mosquito    15 VRVVVRVRPMDKSELDVGSQNVIKVDKSNRSITVVKPNANSSEPPKVYYFDNVFGEDSTQIDLYV 79

  Fly    67 TCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLD--DHVGVIPRAVHDIFTAIAEMQS 129
            ...:..|.|:|.|||.|||||||||:||||||    :|..|  ...|:||.....||..||..:.
Mosquito    80 DTARPIVDKVLEGYNGTILAYGQTGTGKTYTM----SGSADSPQTKGIIPNTFAHIFGHIARGKE 140

  Fly   130 EFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNR----IIMPGLTELVVTSAQQVTDHL 190
            ..:|.|..|::|:|.|:..||. .|..:|:.    |||.|    :.:..|:..||.:|..:.:.:
Mosquito   141 NQKFLVRVSYMEIYNEEVRDLL-GKELNKSL----EVKERADIGVFVKDLSGYVVHNADDLDNIM 200

  Fly   191 IRGSAGRAVAATAMNETSSRSHAIFTLTLVATKLD--GKQSVTTSRFNLVDLAGSERCSKTLASG 253
            ..|:..|.|.||.||..||||||||::|:.:::.|  |:|.|...:..|||||||||.|||.:||
Mosquito   201 KLGNKNRVVGATKMNSESSRSHAIFSITVESSETDEAGRQYVRMGKLQLVDLAGSERQSKTQSSG 265

  Fly   254 DRFKEGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYN 318
            .|.||...||..|..|||||:||..|::. :||||.|||||||||||||||.|:|.|.:||||.|
Mosquito   266 LRLKEATKINLSLSVLGNVISALVDGKST-HIPYRNSKLTRLLQDSLGGNSKTVMCASISPADSN 329

  Fly   319 VAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSG----GKMSSSLISAVG 379
            ..||:||||||.||..|:|...:|.:|..|.:...::.|::|:.:|..|    |..|........
Mosquito   330 YVETISTLRYACRAKSIQNLAHINEEPKDALLRHFQEEIEELKRQLEEGIFQQGIESGDEEEEED 394

  Fly   380 AAGLG-----AIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLD--LTEKEMRA 437
            ..|.|     |:  ||..........|....||:.|..:.|.||.:.:..:.||:  ..|.:...
Mosquito   395 GDGEGEDEEDAV--EEECDPDADRERERLERKEKQRKEKARERKEKSDAEKELLEKKAMENQQEL 457

  Fly   438 HIAEQAHDKLRSHVSELKNK--------LDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRT 494
            ..|:...|:||:.:|.|:||        |::.::.:...||:..:.|.|      .:...||:..
Mosquito   458 KKAKSEQDQLRAKLSSLENKILVGGENLLEKAKEQELLLENSITELEQR------TKTERELKEN 516

  Fly   495 QEELESQGHESRQRLSS-RSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGE-------LRNIN 551
            .:::|::..:..:|.|| :....|.......|..||.|...|..::|.....|       :|:::
Mosquito   517 LQKIEAERIDIEERYSSLQEECVGKTKKLQRVMSMLMSIKSELADQQQEQQREKEGIYENIRSLS 581

  Fly   552 RQLDLKQ--------ELHERIMRNFSRLDSDDEDVKLRLCNQKIDDLEAERRDLMDQLRNIKSKD 608
            |:|.|.:        :.::.::..|:..:.|..:.:|:......:::   |:::.:...|.|..|
Mosquito   582 RELALCELVINSYIPKEYQSMIEKFTHWNEDIGEWQLKCVAYTGNNM---RKNIPEPKVNTKETD 643

  Fly   609 I 609
            :
Mosquito   644 L 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	158/341 (46%)
		Smc	<453..>985	CDD:440809	33/181 (18%)
		Metallothio	<1071..1115	CDD:395080
Klp64D	XP_312517.6	None