Protein Alignment Klp3A and LOC1268741

DIOPT Version :10

• Sequence 1: NP_525053.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: XP_307305.4
• Gene: LOC1268741 / 1268741
• VectorBaseID: AGAMI1_011559
• Length: 683
• Species: Anopheles gambiae
• Alignment Length: 725
• Identity: 265/725 - (36%)
• Similarity: 356/725 - (49%)
• Gaps: 142/725 - (19%)

  Fly     9 VAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNES----YTYNYVFDIDDSQKDLFETCV 69
            |.||:|:||:.|||..|||:..|:::....|.:.|....:    :.|||||.....|..::|..:
Mosquito     7 VKVAVRIRPMSQSEQARGCQTVVKQATPNFPHLLVGNGRTPWHPFAYNYVFPPSALQSQVYEEAI 71

  Fly    70 QAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHVGVIPRAVHDIFTAIAEMQSEFRFA 134
            ...:.||..|||.|||:|||..||||:||||.|.|.:|.:|||||||:::||..||: .:|...|
Mosquito    72 SPMLHKLFAGYNATILSYGQRSSGKTFTMGTDFIGEMDSNVGVIPRAINEIFCLIAD-GTEAAVA 135

  Fly   135 -----VTCSFVELYQEQFYDLFSSKTRD--KATVDIREVK-NRIIMPGLTELVVTSAQQVTDHLI 191
                 :||||:|:||:|.|||.:....|  :..|:|||.. ..||:.||||:.|...|...|.|.
Mosquito   136 LVDTRITCSFIEVYQDQVYDLLTENAIDIERHPVNIREAAGGNIILEGLTEVPVNDKQCALDCLT 200

  Fly   192 RGSAGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTTSRFNLVDLAGSERCSKTLASGDRF 256
            |||.|||....|||..|:|||||||||:..|..|....||.|:|.:||||||||..||.:||.||
Mosquito   201 RGSFGRASRNPAMNNVSTRSHAIFTLTMHHTAKDDPTMVTHSKFRMVDLAGSERSKKTKSSGSRF 265

  Fly   257 KEGVNINKGLLALGNVINALGS--GQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNV 319
            ||||.|||.||||||||.||||  |.:.|:||||.|||||||||||||||.|||||||||.|||:
Mosquito   266 KEGVEINKCLLALGNVITALGSSVGSSKGHIPYRSSKLTRLLQDSLGGNSYTLMIACVSPTDYNL 330

  Fly   320 AETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRVELLSGGKMSSSLISAV--GAAG 382
            ::|.||||||.:...|||||::|.||..|.:..||.:|..:|.|:||..|.....:.|.  |.||
Mosquito   331 SDTYSTLRYASQVRTIKNKPIINQDPPQARIKQLKAIIHDMREEILSLKKDEDKKLGAPQHGNAG 395

  Fly   383 LGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAEQAHDKL 447
            |                  ........:.||:.||.||.:|...:.:|...|:|.
Mosquito   396 L------------------TSSTSPSYKQLQEENRLLQLQLQAKMQELEANEIRV---------- 432

  Fly   448 RSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELESQG---------H 503
                                   |:.|..:.|...|              |:.||         |
Mosquito   433 -----------------------TSADRFLEDIEQL--------------LKPQGKAGVPKDEMH 460

  Fly   504 ESRQRLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQELHERIMRNF 568
            .....|.:|      |....::.|..|...:..|.....|...:|..:.|...|:|..:||..|.
Mosquito   461 SKLAALLAR------EKRSKKIEECWHKLQQLETEVADLFRPSVRIASEQAKFKEEDAKRIAGNL 519

  Fly   569 SRLDSDDEDVKLRLCNQKIDDLEAERRDLMD-------------------QLRNIKSKDISA--- 611
            .|:|. :|..:|   .:::....||.|:|.:                   |:..:....:.|
Mosquito   520 ERIDI-NEPFEL---GRRLAATLAEWRNLTEGNTHDQAVMRRAEAACWVWQIDKVMFSTVKAMVP 580

  Fly   612 --KLAEERRKRLQLLEQ-------------EISDLRRKLITQANLLKIRDKEREKIQNLSTEI-R 660
              ||..||.|:::.:||             :...|||:::.....|:..:.:   |.:|.|.| .
Mosquito   581 LFKLQNERAKKVKHIEQIKAQCARLQEGSAKHKKLRRQILQNETDLEYSNTQ---INDLKTNILA 642

  Fly   661 TMKESKVKLI 670
            |..||..|:|
Mosquito   643 TCSESLPKII 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp3A	NP_525053.1	KISc_KIF4	7..336	CDD:276823	181/340 (53%)
		Smc	<453..>985	CDD:440809	52/265 (20%)
		Metallothio	<1071..1115	CDD:395080
LOC1268741	XP_307305.4	None